Pre-plated Diversity Sets

The Pre-plated Diversity Sets are ideal tools for drug discovery projects that require a wide range of chemical structure dissimilarity and quality drug-like and lead-like compounds to screen against new or validated biological targets from different classes, or where little information is available on a targeted protein structure. For your convenience, there are Diversity Sets of 5,000, 10,000, 15,000, and 20,000 compounds with no structure overlap. They are complementary and can be combined to create more extensive diverse screening libraries (e.g., 30,000, 40,000, and up to 50,000 compounds in total).

Key features:

• 1.Average Tanimoto threshold 0.71-0.77 for separate subsets
• 2.No overlap with our previous Diversity Sets of 50,000 compounds
• 3.Lipinski Rule of Five and Veber criteria compliant compounds
• 4.No reagents. No reactive and unstable molecules
• 5.PAINS filters families A, B, C applied
• 6.Lilly MedChem Rules compliant