Anti-Cardiovascular Disease Compound Library

カタログ番号 L5400

ライブラリー構成化合物リスト Excel SDF

Cardiovascular disease generally refers to all types of diseases that affect the heart or blood vessels, including coronary heart disease (clogged arteries), which can cause heart attacks, stroke, congenital heart defects and peripheral artery disease, and is the leading cause of death for men and women in the U.S. Different types of cardiovascular diseases have different mechanisms of pathogenesis. Antioxidants, lipid-lowering agents, anti-ischemic drugs, and platelet aggregation inhibitors all can reduce cardiovascular disease risk. Some natural products can inhibit the gene expression of cell adhesion molecules, cytokine, and chemokine, inhibit the function of platelet, enhance the release of nitric oxide by endothelial cells, and inhibit the contraction of smooth muscle.

A unique collection of 1428 cardiovascular diseases related compounds by TargetMol can be used for cardiovascular diseases related research and high throughput and high content screening for new drugs.

TargetMolの製品は全て研究用試薬です。人体にはご使用できません。また、個人の方への販売は行っておりません。

パッケージサイズ
1 mg
30 μL * 10 mM (in DMSO)
50 μL * 10 mM (in DMSO)
100 μL * 10 mM (in DMSO)
250 μL * 10 mM (in DMSO)

お問い合わせはこちら

If the above compound libraries do not match your needs,
please contact our compound library specialist for a customized compound library at [email protected]

ライブラリ構成化合物リストを依頼する

製品概要

ハイスループットスクリーニング（HTS）およびハイコンテンツスクリーニング（HCS）に最適な1428種類の心血管疾患関連化合物の独自コレクション
非臨床前試験および臨床試験において生物活性と安全性が確認済みであり、ほとんどの化合物は米国FDA、EMA、中国FDAにより承認済み
膜トランスポーターやイオンチャネルなど、主要なターゲットを多岐に渡りカバーする心血管疾患の研究において有効なツール
化合物の概要、化学構造、標的、IC50値、生物活性など詳細な情報を提供
構造的多様性、薬効、細胞膜透過性を有する化合物
NMRとHPLC/LCMSにより高純度と高品質を担保

ライブラリーのカスタマイズ

TargetMol社化合物ライブラリーは自由にカスタマイズできます! もっと詳しく

梱包・保管

バーコード付き貯蔵管や96/384-wellプレートに入っている粉末固体またはDMSO溶液
ブルーアイス同梱にて出荷

サポートファイル

ライブラリーの取扱説明書 (635 KB) TargetMol のライブラリーカタログ (13.2 MB) ExcelおよびSDFファイル形式でのライブラリー構成化合物リストの要求

Publications Cited TargetMol Libraries

1. Cell Stem Cell. 2022 Apr 29(4) 545–558. 2. Science Bulletin. 2022. 3. Science Translational Medicine. 2022, 14(656): eabn3231. 4. Science Advances. 2023, 9(9): eade3760. 5. Nature. 2020, 582: 289-293. 6. Nature Biotechnology. 2021, 39(11): 1444-1452. 7. Nature Communications. 2022, 13(1): 1-15.. 8. Nature Communications. 2023, 14(1): 1020.. 9. Nature Communications. 2023, 14(1): 2756..

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Empty	1001625-82-6	1001645-58-4	1001753-24-7	1001908-89-9	1002304-34-8	1002-84-2	100291-86-9	100299-08-9	10030-52-1	10040-45-6	Empty
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Empty	100427-26-7	1004316-88-4	10045-45-1	100462-37-1	1004990-28-6	100-51-6	1005-24-9	1005264-47-0	1005334-57-5	1005342-46-0	Empty
Empty	Lercanidipine	Cobicistat	1-Ethyl-2-benzimidazolinone	ROSIRIDIN	PF-AKT400	Benzyl alcohol	1-Methylnicotinamide chloride	MX69	CVT-10216	LCL161	Empty
Empty	1005491-05-3	100-55-0	1005504-62-0	1005883-72-6	100643-71-8	1007207-67-1	10075-50-0	1007647-73-5	100784-20-1	10083-24-6	Empty
Empty	Tirasemtiv	Roniacol	Rg3039	Z433927330	Desloratadine	CH5132799	5-Bromoindole	Smurf1-IN-A01	Halosulfuron-methyl	Piceatannol	Empty
Empty	100872-83-1	100874-08-6	1009119-64-5	1009119-65-6	100929-71-3	1009298-09-2	1009298-59-2	100929-99-5	1009734-33-1	10097-84-4	Empty
Empty	ML346	SB 4	Daclatasvir	Daclatasvir dihydrochloride	NADPH (tetracyclohexanamine)	AZD8055	Vistusertib	PAβN dihydrochloride	HZ1157	Rotundine	Empty
Empty	1009816-48-1	1009817-63-3	1009820-21-6	100986-85-4	101001-34-7	1010411-21-8	1010-60-2	1011244-68-0	1011301-27-1	1011529-10-4	Empty
Empty	Thiamet G	B-AP15	Silmitasertib	Levofloxacin	Pamicogrel	GSK369796 Dihydrochloride	2-Chloronaphthoquinone	TFAP	Tenovin3	Azvudine	Empty
Empty	101152-94-7	101155-02-6	1011557-82-6	1011-74-1	101-20-2	1012054-59-9	101-21-3	101-26-8	101303-98-4	1013101-36-4	Empty
Empty	Milnacipran hydrochloride	BW-A78U	Tenovin-6	DL-Normetanephrine hydrochloride	Triclocarban	CUDC101	Chlorpropham	Mestinon	Zacopride hydrochloride	PF04691502	Empty
Empty	101-31-5	1013-69-0	1013750-77-0	1013753-99-5	10138-52-0	1013920-15-4	1013937-63-7	1014691-61-2	101477-54-7	101494-95-5	Empty
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