Human endogenous metabolites, which are produced and found within the human body, primarily include carbohydrates, bioactive peptides, nucleosides and nucleic acids, endogenous regulatory factors, cytokines, and proteins. These metabolites are often involved in essential physiological processes in the body, exerting specific physiological functions and biological activities.
Human endogenous metabolites can serve as diagnostic biomarkers. For instance, in the field of cancer research, methods for malignant tumors diagnose, drug screening, and drug toxicity assessment based on the abnormal changes in characteristic small-molecule metabolic biomarkers inside and outside tumor cells have become a hotspot for research. In addition to their role as biomarkers, human endogenous metabolites also play crucial physiological roles. Numerous research results confirms that there is a close relationship between many diseases and the alterations in endogenous substances. Therefore, investigating endogenously active compounds as a starting point for finding drugs to treat diseases has become one of the primary approaches in drug research.
The TargetMol’s Human Endogenous Metabolite Library consists of a selection of 508 human endogenous metabolites, serving as effective tools for exploring the disease mechanisms and discovering new drugs.
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