ホーム 計算ツール
代理店ログイン

Inhibitor Library

カタログ番号 L2000
  ライブラリー構成化合物リスト   Excel SDF

Cell signalingis part of any communication process that governs basic activities of cells and coordinates all cell actions. The ability of cells to perceive and correctly respond to their microenvironment is the basis of development,tissue repair, andimmunity, as well as normal tissuehomeostasis. Errors in signaling interactions and cellularinformation processingare responsible for diseases such as cancer,auto-immunity, and diabetes.By understanding cell signaling, diseases may be treated more effectively.

Inhibitor library is a unique collection of 8418 compounds, each of which has clear inhibitory targets. It is an effective tool for research in cell signaling pathways and related diseases, and high throughput screening and high content screening for new drugs.

TargetMolの製品は全て研究用試薬です。人体にはご使用できません。 また、個人の方への販売は行っておりません。
パッケージサイズ
1 mg
30 μL * 10 mM (in DMSO)
50 μL * 10 mM (in DMSO)
100 μL * 10 mM (in DMSO)
250 μL * 10 mM (in DMSO)
If the above compound libraries do not match your needs,
please contact our compound library specialist for a customized compound library at [email protected]
ライブラリ構成化合物リストを依頼する
Get quote

製品概要

  • 細胞内シグナル伝達に有用な8418種類の阻害剤を独自に収集したライブラリーで、新薬探索のハイスループットスクリーニング(HTS)およびハイコンテンツスクリーニング(HCS)に最適
  • 非臨床試験および臨床試験において生物活性と安全性が確認済みで、一部に承認薬を含む
  • ターゲットにはMAPK、PI3K、JAK、HDAC、VEGFR、CDKなど
  • 構造的多様性、薬効、細胞膜透過性を有する化合物
  • 化合物の概要、化学構造、標的、生物活性、IC50など詳細な情報を提供
  • NMRとHPLCなどの品質管理により適正な構造と高純度を担保

ライブラリーのカスタマイズ

TargetMol社化合物ライブラリーは自由にカスタマイズできます! もっと詳しく

梱包・保管

  • バーコード付き貯蔵管や96/384-wellプレートに入っている粉末固体またはDMSO溶液
  • ブルーアイス同梱にて出荷
ライブラリ構成化合物複合リストをリクエスト (L2000)

Publications Cited TargetMol Libraries

隠し

ライブラリーの構成

Apoptosis (787)
Autophagy (560)
Antibacterial (329)
5-HT Receptor (225)
CDK (214)
COX (186)
Endogenous Metabolite (184)
PI3K (180)
Antibiotic (173)
EGFR (171)
HIV Protease (167)
DNA/RNA Synthesis (164)
AChR (157)
VEGFR (156)
NF-κB (152)
PDE (150)
Dopamine Receptor (145)
Epigenetic Reader Domain (142)
Dehydrogenase (135)
P450 (128)
Adrenergic Receptor (126)
HDAC (122)
Histone Methyltransferase (121)
Histamine Receptor (117)
Parasite (116)
Potassium Channel (112)
JAK (103)
Calcium Channel (103)
mTOR (100)
FLT (99)
Phosphatase (98)
Antifungal (98)
Src (94)
Sodium Channel (91)
PDGFR (91)
Microtubule Associated (87)
Topoisomerase (83)
TRP/TRPV Channel (80)
FGFR (80)
PARP (79)
Raf (78)
AChE (77)
Wnt/beta-catenin (77)
ERK (75)
c-Kit (75)
SARS-CoV (75)
PKC (75)
Influenza Virus (74)
Akt (73)
p38 MAPK (72)
GSK-3 (72)
STAT (71)
HCV Protease (70)
Ras (69)
c-Met/HGFR (65)
MAO (65)
Proteasome (64)
Bcr-Abl (63)
RAAS (63)
Prostaglandin Receptor (62)
TNF (60)
Ferroptosis (60)
Reactive Oxygen Species (58)
Lipoxygenase (58)
ALK (57)
Aurora Kinase (57)
MMP (55)
GABA Receptor (55)
BCL (55)
Phospholipase (55)
HSP (54)
BTK (53)
DUB (52)
TGF-beta/Smad (50)
Virus Protease (47)
MAPK (47)
Casein Kinase (46)
Tyrosinase (46)
ROCK (46)
Tyrosine Kinases (46)
Adenosine Receptor (46)
Transferase (46)
NMDAR (45)
E1/E2/E3 Enzyme (45)
ATPase (44)
MEK (44)
Monoamine Oxidase (43)
NO Synthase (42)
Caspase (42)
HER (42)
Serine/threonin kinase (41)
Beta Amyloid (41)
iGluR (41)
GluR (41)
Histone Demethylase (41)
IL Receptor (41)
CCR (39)
Mitophagy (39)
HSV (39)
PKA (38)
JNK (38)
Sirtuin (38)
DNA-PK (38)
Reverse Transcriptase (38)
c-RET (37)
PPAR (37)
Mitochondrial Metabolism (37)
Cysteine Protease (37)
GPR (37)
Carbonic Anhydrase (37)
AMPK (36)
Serotonin Transporter (36)
TAM Receptor (35)
Antioxidant (35)
IκB/IKK (35)
Integrin (34)
HBV (34)
HIF (33)
Nucleoside Antimetabolite/Analog (33)
IGF-1R (33)
P-gp (33)
NOS (32)
ROS (32)
Gamma-secretase (32)
RIP kinase (31)
Drug Metabolite (31)
Proton pump (30)
Serine Protease (30)
Norepinephrine (30)
CXCR (30)
Histone Acetyltransferase (30)
CaMK (29)
PLK (29)
c-Fms (29)
Androgen Receptor (29)
S6 Kinase (29)
Estrogen Receptor/ERR (29)
Glucosidase (29)
TLR (29)
Estrogen/progestogen Receptor (28)
HIF/HIF Prolyl-Hydroxylase (28)
Reductase (28)
Trk receptor (27)
Interleukin (27)
FAAH (26)
P2X Receptor (26)
Hedgehog/Smoothened (26)
Antiviral (25)
Pim (25)
Syk (25)
DPP-4 (24)
Glucocorticoid Receptor (24)
Acyltransferase (24)
p53 (24)
FAK (24)
ATM/ATR (24)
Chk (23)
Kinesin (23)
Fatty Acid Synthase (22)
Indoleamine 2,3-Dioxygenase (IDO) (22)
NOD (21)
Cannabinoid Receptor (21)
SGLT (21)
Mdm2 (21)
DYRK (21)
Opioid Receptor (21)
HMG-CoA Reductase (21)
Anti-infection (20)
Thrombin (20)
S1P Receptor (20)
IRAK (20)
Neurokinin receptor (19)
Xanthine Oxidase (19)
LRRK2 (19)
transporter (19)
PDK (19)
LPL Receptor (19)
NADPH (19)
Chloride channel (19)
Antifection (18)
Rho (18)
Lipase (18)
DNA Methyltransferase (18)
Factor Xa (17)
PAK (17)
Endothelin Receptor (17)
Smo (17)
Nrf2 (17)
MRP (17)
Hydroxylase (16)
LTR (16)
Epoxide Hydrolase (16)
PD-1/PD-L1 (15)
PERK (15)
Aromatase (15)
Immunology/Inflammation related (15)
Glutathione Peroxidase (15)
P2Y Receptor (15)
IRE1 (15)
BACE (15)
PI4K (15)
YAP (14)
Retinoid Receptor (14)
OX Receptor (14)
Complement System (14)
Leukotriene Receptor (14)
DHFR (14)
ribosome (14)
Myosin (14)
CSF-1R (14)
Glucokinase (14)
Aryl Hydrocarbon Receptor (13)
Sigma receptor (13)
cAMP (13)
ROS Kinase (13)
c-Myc (13)
GTPase (13)
Ephrin Receptor (12)
LPA Receptor (12)
Neuropeptide Y Receptor (12)
AhR (12)
PGE Synthase (12)
Protease-activated Receptor (12)
Aminopeptidase (12)
DNA gyrase (11)
Stearoyl-CoA Desaturase (SCD) (11)
Lipid (11)
Monoamine Transporter (11)
Isocitrate Dehydrogenase (IDH) (11)
NOD-like Receptor (NLR) (11)
Antifolate (11)
Discoidin Domain Receptor (DDR) (11)
Beta-Secretase (11)
CETP (10)
Monocarboxylate transporter (10)
cholecystokinin (10)
PAI-1 (10)
IDO (10)
Acetyl-CoA Carboxylase (10)
DNA (10)
Vasopressin Receptor (10)
ATP Citrate Lyase (9)
Platelet aggregation (9)
STING (9)
GRK (9)
SGK (9)
Glutaminase (9)
Telomerase (9)
MLK (9)
IAP (9)
RSV (8)
CFTR (8)
MNK (8)
NAMPT (8)
ASK (8)
Neprilysin (8)
NADPH-oxidase (8)
BCRP (8)
Porcupine (8)
Phosphorylase (8)
GPX (7)
p97 (7)
Carboxypeptidase (7)
MAGL (7)
ABC (7)
UGT (7)
Adenylyl cyclase (7)
Dynamin (7)
Wee1 (7)
DNA Alkylator/Crosslinker (7)
Na+/Ca2+ Exchanger (7)
PAD (7)
Tie-2 (7)
GlyT (7)
Angiotensin-converting Enzyme (ACE) (7)
SIK (7)
GST (6)
AAK1 (AP2 associated kinase 1) (6)
OAT (6)
LDL (6)
FLAP (6)
MELK (6)
Progesterone Receptor (6)
Guanylate cyclase (6)
Thyroid hormone receptor(THR) (6)
DNA Alkylation (6)
Bombesin Receptor (5)
Survivin (5)
CRISPR/Cas9 (5)
Aquaporin (5)
Melanocortin Receptor (5)
LIM Kinase (5)
Neurotensin Receptor (5)
Adenosine deaminase (5)
PAFR (5)
MTH1 (5)
PTEN (5)
TOPK (5)
BMI-1 (5)
ACK (5)
DprE1 (5)
PYK2 (5)
Decarboxylase (5)
cGAS (5)
CRFR (5)
NPC1L1 (5)
Methionine Adenosyltransferase (MAT) (5)
APC (5)
Hippo pathway (5)
CRM1 (5)
OXPHOS (4)
NEDD8 (4)
DAPK (4)
KSP (4)
ROR (4)
Amino Acids and Derivatives (4)
Galectin (4)
CGRP Receptor (4)
GNRH Receptor (4)
MALT (4)
Imidazoline Receptor (4)
PKM (4)
advanced glycation end products (4)
MyD88 (4)
VDAC (4)
CD73 (4)
Amylase (4)
Protease (4)
Glucagon Receptor (4)
Bradykinin Receptor (4)
MT Receptor (4)
Gap Junction Protein (3)
Arginase (3)
Ligand for E3 Ligase (3)
Hexokinase (3)
CaSR (3)
Necroptosis (3)
Liver X Receptor (3)
Hck (3)
HCN Channel (3)
Pyroptosis (3)
Transaminase (3)
Haspin Kinase (3)
CAT (3)
IFNAR (3)
Melatonin Receptor (3)
Arrestin (2)
AIM2 (2)
EBI2/GPR183 (2)
Na-K-Cl cotransporter (2)
NUDIX hydrolase (2)
Integrase (2)
CD38 (2)
Melanin-concentrating Hormone Receptor (MCHR) (2)
GSNOR (2)
hCE (2)
FOXO1 (2)
GHSR (2)
FXR (2)
KLF (2)
Oxytocin Receptor (2)
Prolyl Endopeptidase (PREP) (2)
gp120/CD4 (2)
Cell wall (1)
PGC-1α (1)
GluCls (1)
Adiponectin receptor (1)
stilbene oxidase (1)
Stemness kinase (1)
Annexin A (1)
Glutathione reductase (1)
TSH Receptor (1)
Taste receptor (1)
Apelin receptor (1)
RANKL/RANK (1)
N-Acetylglucosaminyltransferase (1)
Anion Exchanger (1)
lysosomal autophagy (1)
FKBP (1)
aconitase (1)
Neuropeptide W (1)
Somatostatin (1)
LHRH (1)
Fer/FerT kinase (1)
VDA (1)
Procollagen C Proteinase (1)
GPCR19 (1)
FABP (1)
Ligands for Target Protein for PROTAC (1)
Fas/FasL (1)
Thioredoxin (1)
CPT (1)
OCT (1)
RAR/RXR  (1)

化合物ライブラリー情報実例

Empty 1000025-07-9 1000413-72-8 229005-80-5 1000787-75-6 946387-07-1 1000998-59-3 1175526-27-8 1001288-58-9 1001350-96-4 1001404-83-6 Empty
Vadadustat TAK875 TAK-779 Tegobuvir RN-1734 BMS-687453 AM211 FT011 BMS754807 AAI101
Empty 1001625-82-6 1001645-58-4 1001753-24-7 1001908-89-9 1002304-34-8 1002-84-2 100291-86-9 100299-08-9 10030-52-1 10040-45-6 Empty
RPW-24 SRT1720 hydrochloride INH6 SRT 2183 AMG208 Pentadecanoic acid Apiopaeonoside Pemirolast potassium L-Anserine nitrate salt Sodium Picosulfate
Empty 100427-26-7 1004316-88-4 10045-45-1 100462-37-1 1004990-28-6 100-51-6 1005-24-9 1005264-47-0 1005334-57-5 1005342-46-0 Empty
Lercanidipine Cobicistat 1-Ethyl-2-benzimidazolinone ROSIRIDIN PF-AKT400 Benzyl alcohol 1-Methylnicotinamide chloride MX69 CVT-10216 LCL161
Empty 1005491-05-3 100-55-0 1005504-62-0 1005883-72-6 100643-71-8 1007207-67-1 10075-50-0 1007647-73-5 100784-20-1 10083-24-6 Empty
Tirasemtiv Roniacol Rg3039 Z433927330 Desloratadine CH5132799 5-Bromoindole Smurf1-IN-A01 Halosulfuron-methyl Piceatannol
Empty 100872-83-1 100874-08-6 1009119-64-5 1009119-65-6 100929-71-3 1009298-09-2 1009298-59-2 100929-99-5 1009734-33-1 10097-84-4 Empty
ML346 SB 4 Daclatasvir Daclatasvir dihydrochloride NADPH (tetracyclohexanamine) AZD8055 Vistusertib PAβN dihydrochloride HZ1157 Rotundine
Empty 1009816-48-1 1009817-63-3 1009820-21-6 100986-85-4 101001-34-7 1010411-21-8 1010-60-2 1011244-68-0 1011301-27-1 1011529-10-4 Empty
Thiamet G B-AP15 Silmitasertib Levofloxacin Pamicogrel GSK369796 Dihydrochloride 2-Chloronaphthoquinone TFAP Tenovin3 Azvudine
Empty 101152-94-7 101155-02-6 1011557-82-6 1011-74-1 101-20-2 1012054-59-9 101-21-3 101-26-8 101303-98-4 1013101-36-4 Empty
Milnacipran hydrochloride BW-A78U Tenovin-6 DL-Normetanephrine hydrochloride Triclocarban CUDC101 Chlorpropham Mestinon Zacopride hydrochloride PF04691502
Empty 101-31-5 1013-69-0 1013750-77-0 1013753-99-5 10138-52-0 1013920-15-4 1013937-63-7 1014691-61-2 101477-54-7 101494-95-5 Empty
L-Hyoscyamine Noreugenin ML-030 BC-1382 Gadolinium chloride Vorolanib VTP-27999 TFA GSK0660 Lomerizine hydrochloride 8-CHLOROQUINAZOLIN-4(1H)-ONE