Powder: -20°C for 3 years | In solvent: -80°C for 1 year
ABT-670 is a selective agonist of dopamine D4 receptor. For human D4, ferret D4, and rat D4, the EC50 values are 89 nM, 160 nM, and 93 nM , respectively.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
25 mg | 約6-8 週間 | ¥ 349,000 |
50 mg | 約6-8 週間 | ¥ 454,500 |
100 mg | 約6-8 週間 | ¥ 574,000 |
ターゲット&IC50 | D4 (Ferret):160 nM(EC50), D4 (human):(EC50)89 nM, D4 (rat):93 nM(EC50) |
In vivo | ABT-670, at a dosage of 0.1 μmol/kg, significantly promotes a high incidence (75%) of erections in male rats, demonstrating robust efficacy. Furthermore, it displays exceptional oral bioavailability across multiple species—rat (68%), dog (85%), and monkey (91%)—while maintaining comparable efficacy, safety, and tolerability[1]. |
分子量 | 325.4 |
分子式 | C19H23N3O2 |
CAS No. | 630119-43-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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ABT-670 630119-43-6 GPCR/G Protein Neuroscience Dopamine Receptor ABT670 ABT 670 Inhibitor inhibitor inhibit