Powder: -20°C for 3 years | In solvent: -80°C for 1 year
APS6-45 inhibits RAS/MAPK signaling and exhibits anti-tumor activity.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 17,000 | |||
5 mg | 在庫あり | ¥ 41,000 | |||
10 mg | 在庫あり | ¥ 66,500 | |||
25 mg | 在庫あり | ¥ 121,500 | |||
50 mg | 在庫あり | ¥ 176,500 | |||
100 mg | 在庫あり | ¥ 248,000 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 50,000 |
説明 | APS6-45 inhibits RAS/MAPK signaling and exhibits anti-tumor activity. |
In vitro | APS6-45 (1 μM; 1 h) strongly inhibits RAS pathway activity signaling in human MTC cell lines TT and MZ-CRC-1[1]. |
In vivo | APS6-45 did not affect body weight of dosed(10 mg/kg) mice after 30 d.APS6-45 (0.1-160 mg/kg; a single p.o.) does not cause detectable toxic effects in mice[1]. |
分子量 | 548.39 |
分子式 | C23H16F8N4O3 |
CAS No. | 2188236-41-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 240mg/mL (437.67mM)
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
APS6-45 2188236-41-9 GPCR/G Protein MAPK Ras calibrated signaling TCI Inhibitor APS-6-45 APS645 Carcinoma Thyroid antitumor Medullary APS6 45 tumor inhibit inhibitor