store at low temperature
store at -20°C
Adalimumab (anti-TNF-alpha) is the first fully human recombinant IgG1 monoclonal antibody that specifically targets human TNF-alpha.
説明 | Adalimumab (anti-TNF-alpha) is the first fully human recombinant IgG1 monoclonal antibody that specifically targets human TNF-alpha. |
細胞研究 | Objective: Adalimumab induces apoptosis of THP-1 cells. Concentrations: 10μg/mL. Incubation Time: 6, 12, 18, 24, 30 hours. Method: THP-1 cells (0.5×106) were incubated with anti-FcRI mAb and anti-FcRII mAb, and then cultured with adalimumab, infliximab, huIgG or vehicle (PBS) alone as indicated. LPS (1μg/mL) was added in all culture conditions. Apoptosis was analyzed at different time points by staining with annexin V-FITC and propidium iodide, Apo2.7-PE-conjugated antibody, or 7AAD. |
動物実験 | Objective: The distribution of certolizumab pegol, adalimumab, and infliximab in the inflamed paws of mice with collagen-induced arthritis. Formulation: PBS. Dosages: 2 mg/kg |
分子量 | 148 kDa |
CAS No. | 331731-18-1 |
store at low temperature
store at -20°C
DMSO: Insoluble
H2O: 10 mM
You can also refer to dose conversion for different animals. 詳細
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Adalimumab 331731-18-1 Apoptosis TNF Inhibitor inhibitor inhibit