Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Arnicolide D is a sesquiterpene lactone. Arnicolide D isolates from Centipeda minima. Arnicolide D modulates the cell cycle, activates the caspase signaling pathway and inhibits the PI3K/AKT/mTOR and STAT3 signaling pathways. Arnicolide D inhibits Nasopharyngeal carcinoma (NPC) cell viability in a concentration- and time-dependent manner. Arnicolide D exerts strong cytotoxic activity on the human colon carcinoma HT-29 cell line.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 35,500 | |||
5 mg | 在庫あり | ¥ 108,500 | |||
10 mg | 在庫あり | ¥ 156,000 | |||
25 mg | 在庫あり | ¥ 226,500 | |||
50 mg | 在庫あり | ¥ 317,000 |
説明 | Arnicolide D is a sesquiterpene lactone. Arnicolide D isolates from Centipeda minima. Arnicolide D modulates the cell cycle, activates the caspase signaling pathway and inhibits the PI3K/AKT/mTOR and STAT3 signaling pathways. Arnicolide D inhibits Nasopharyngeal carcinoma (NPC) cell viability in a concentration- and time-dependent manner. Arnicolide D exerts strong cytotoxic activity on the human colon carcinoma HT-29 cell line. |
In vitro | In this study, we found that two sesquiterpene lactones, isobutyroylplenolin and Arnicolide D, from Centipeda minima L. (Compositae) exerted stronger cytotoxic activity than cisplatin on the human colon carcinoma HT-29 cell line. Furthermore, the cytotoxicity of these two compounds on normal cells was weaker than that of cisplatin. |
植物由来 |
分子量 | 332.39 |
分子式 | C19H24O5 |
CAS No. | 34532-68-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 2.75 mg/mL (8.27 mM)
You can also refer to dose conversion for different animals. 詳細
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Arnicolide D 34532-68-8 Apoptosis Cytoskeletal Signaling JAK/STAT signaling PI3K/Akt/mTOR signaling Proteases/Proteasome Stem Cells PI3K Akt Caspase STAT mTOR Mammalian target of Rapamycin Phosphoinositide 3-kinase inhibit Inhibitor PKB Protein kinase B inhibitor