Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CDK9-IN-7 is a highly selective and orally active CDK9/cyclin T inhibitor (IC50: 11 nM), which exhibits more potent over other CDKs (CDK4/cyclinD: 148 nM; CDK6/cyclinD: 145 nM).
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
無料サンプル 1 mg | |||||
1 mg | 在庫あり | ¥ 45,500 | |||
5 mg | 在庫あり | ¥ 120,000 | |||
10 mg | 在庫あり | ¥ 174,500 | |||
25 mg | 在庫あり | ¥ 268,500 | |||
50 mg | 在庫あり | ¥ 363,000 | |||
100 mg | 在庫あり | ¥ 489,000 | |||
500 mg | 在庫あり | ¥ 980,000 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 131,500 |
説明 | CDK9-IN-7 is a highly selective and orally active CDK9/cyclin T inhibitor (IC50: 11 nM), which exhibits more potent over other CDKs (CDK4/cyclinD: 148 nM; CDK6/cyclinD: 145 nM). |
ターゲット&IC50 | CDK6/cyclinD:145 nM, CDK4/cyclin D:148 nM, CDK9/CyclinT1:11 nM |
In vitro | CDK9-IN-7 (compound 21e) displays exceptional potency against NSCLC cell lines, especially A549 and H1299 with IC50 values less than 0.5 µM. In the drug-resistant NSCLC cell line H1975, CDK9-IN-7 also exhibits good inhibition potency (IC50: 0.837 µM)[1]. |
分子量 | 547.71 |
分子式 | C29H37N7O2S |
CAS No. | 2369981-71-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 56.7mg/mL (103.5mM), sonification is recommended.
You can also refer to dose conversion for different animals. 詳細
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CDK9-IN-7 2369981-71-3 Cell Cycle/Checkpoint CDK CDK-9-IN-7 CDK9IN7 CDK9 IN 7 Inhibitor inhibitor inhibit