Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CGP60474 is an inhibitor of VEGFR-2 (IC50 = 84 nM) and an inhibitor of ATP-competitive PKC. CGP60474 is also a highly potent anti-endotoxemic agent and inhibits cyclin-dependent kinase (CDK) potently.
説明 | CGP60474 is an inhibitor of VEGFR-2 (IC50 = 84 nM) and an inhibitor of ATP-competitive PKC. CGP60474 is also a highly potent anti-endotoxemic agent and inhibits cyclin-dependent kinase (CDK) potently. |
ターゲット&IC50 | CDK9-CyclinT:13 nM, CDK5-p25:10 nM, CDK4-CyclinD:216 nM, CDK2-CyclinE:3 nM, CDK7-CyclinH:200 nM, CDK2-CyclinA:4 nM, CDK1-CyclinB:26 nM, VEGFR2:84 nM |
分子量 | 355.82 |
分子式 | C18H18ClN5O |
CAS No. | 164658-13-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (140.52 mM)
H2O: < 0.1 mg/mL (insoluble)
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
CGP60474 164658-13-3 Angiogenesis Cell Cycle/Checkpoint Chromatin/Epigenetic Cytoskeletal Signaling Tyrosine Kinase/Adaptors VEGFR CDK PKC inhibit endotoxemic CGP-60474 Cyclin dependent kinase LPS Inhibitor Protein kinase C selective survival ATP-competitive IL-6 level CGP 60474 inhibitor