Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CHIR 98024 is a potent GSK-3α/β inhibitor with IC50 of 0.65 nM/0.58 nM in cell-free assays, with the ability to distinguish GSK-3 from its closest homologs Cdc2 and ERK2.
説明 | CHIR 98024 is a potent GSK-3α/β inhibitor with IC50 of 0.65 nM/0.58 nM in cell-free assays, with the ability to distinguish GSK-3 from its closest homologs Cdc2 and ERK2. |
ターゲット&IC50 | GSK-3α:0.65 nM, GSK-3β:0.58 nM |
別名 | CHIR98014 |
分子量 | 486.31 |
分子式 | C20H17Cl2N9O2 |
CAS No. | 556813-39-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: < 1 mg/mL (insoluble or slightly soluble)
DMSO: 8 mg/mL
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
CHIR 98024 556813-39-9 MAPK PI3K/Akt/mTOR signaling Stem Cells GSK-3 S6 Kinase inhibit ischemic stroke CHIR98024 Glycogen synthase kinase 3 CHIR-98024 Inhibitor CHIR 98014 Glycogen synthase kinase-3 CHIR98014 CHIR-98014 inhibitor