Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CM-579 is a dual inhibitor of G9a and DNMT( IC50:16 nM, 32 nM for G9a and DNMT). It has potent in vitro cellular activity in a wide range of cancer cells.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 11,500 | |||
5 mg | 在庫あり | ¥ 22,500 | |||
10 mg | 在庫あり | ¥ 32,500 | |||
25 mg | 在庫あり | ¥ 52,500 | |||
50 mg | 在庫あり | ¥ 77,500 | |||
100 mg | 在庫あり | ¥ 114,000 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 29,000 |
説明 | CM-579 is a dual inhibitor of G9a and DNMT( IC50:16 nM, 32 nM for G9a and DNMT). It has potent in vitro cellular activity in a wide range of cancer cells. |
ターゲット&IC50 | DNMT3B:1000 nM, G9a:16 nM, DNMT3A:92 nM, DNA methyltransferase:32 nM, DNMT1:1.5 nM (kd) |
In vitro | CM-579 inhibits DNMT3A and DNMT3B ( IC50s: 92 nM and 1000 nM). The Kd of CM-579 for DNMT1 is 1.5 nM. [1] |
分子量 | 492.65 |
分子式 | C29H40N4O3 |
CAS No. | 1846570-40-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 45 mg/mL (91.34 mM)
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
CM-579 1846570-40-8 Chromatin/Epigenetic DNA Methyltransferase Histone Methyltransferase CM 579 CM579 Inhibitor inhibitor inhibit