Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DB07107 is a potent inhibitor of drug resistant T315I mutant Bcr-Abl tyrosine kinase and a potent Akt1 inhibitor (IC50: 360 nM).
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
25 mg | 約6-8 週間 | ¥ 349,000 |
50 mg | 約6-8 週間 | ¥ 454,500 |
100 mg | 約6-8 週間 | ¥ 574,000 |
説明 | DB07107 is a potent inhibitor of drug resistant T315I mutant Bcr-Abl tyrosine kinase and a potent Akt1 inhibitor (IC50: 360 nM). |
ターゲット&IC50 | Akt1:360 nM |
In vitro | DB07107 from DrugBank showed the highest binding energy (XP: -14.045 kcal/mol). DB07107 is more potent in blocking drug-resistant T315I mutant than the wild-type Bcr-Abl [1]. |
分子量 | 370.45 |
分子式 | C23H22N4O |
CAS No. | 552332-71-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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DB07107 552332-71-5 Cytoskeletal Signaling PI3K/Akt/mTOR signaling Akt DB-07107 DB 07107 Inhibitor inhibitor inhibit