Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Darunavir (TMC114) is an HIV PROTEASE INHIBITOR that is used in the treatment of AIDS and HIV INFECTIONS. Due to the emergence of ANTIVIRAL DRUG RESISTANCE when used alone, it is administered in combination with other ANTI-HIV AGENTS.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
5 mg | 在庫あり | ¥ 9,500 | |||
10 mg | 在庫あり | ¥ 13,000 | |||
25 mg | 在庫あり | ¥ 21,500 | |||
50 mg | 在庫あり | ¥ 32,000 | |||
100 mg | 在庫あり | ¥ 45,500 | |||
500 mg | 在庫あり | ¥ 117,500 |
説明 | Darunavir (TMC114) is an HIV PROTEASE INHIBITOR that is used in the treatment of AIDS and HIV INFECTIONS. Due to the emergence of ANTIVIRAL DRUG RESISTANCE when used alone, it is administered in combination with other ANTI-HIV AGENTS. |
In vivo | Vipadenant (0.3-30 mg/kg) produces a dose-dependent reduction in catalepsy. Vipadenant (10 mg/kg) does not produce any statistically significant dyskinetic episodes in 6-OHDA-lesioned rats during a 19-day dosing regimen[1]. In the mouse and rat haloperidol-induced hypolocomotion models, vipadenant has a minimum effective dose of 0.1 and 1 mg/kg, respectively. Vipadenant (3 and 10 mg/kg, p.o.) is able to increase contralateral rotations in 6-OHDA lesioned rats[2]. |
別名 | TMC114 |
分子量 | 547.66 |
分子式 | C27H37N3O7S |
CAS No. | 206361-99-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethanol: 35 mg/mL (78.14 mM)
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Darunavir 206361-99-1 Microbiology/Virology Proteases/Proteasome HIV Protease TMC114 AID Minimal TMC-114 cytotoxicity UIC 94017 Human immunodeficiency virus UIC94017 Inhibitor inhibit HIV UIC-94017 TMC 114 inhibitor