Powder: -20°C for 3 years | In solvent: -80°C for 1 year
GSK-1070916 (GSK-1070916A) is a reversible and ATP-competitive inhibitor of Aurora B/C with IC50 of 3.5 nM/6.5 nM. It displays >100-fold selectivity against the closely related Aurora A-TPX2 complex. Phase 1.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 9,500 | |||
5 mg | 在庫あり | ¥ 22,000 | |||
10 mg | 在庫あり | ¥ 37,500 | |||
25 mg | 在庫あり | ¥ 64,000 | |||
50 mg | 在庫あり | ¥ 100,500 | |||
100 mg | 在庫あり | ¥ 149,000 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 25,000 |
説明 | GSK-1070916 (GSK-1070916A) is a reversible and ATP-competitive inhibitor of Aurora B/C with IC50 of 3.5 nM/6.5 nM. It displays >100-fold selectivity against the closely related Aurora A-TPX2 complex. Phase 1. |
ターゲット&IC50 | Aurora C-INCENP:6.5 nM, Aurora B-INCENP:3.5 nM |
別名 | GSK-1070916A, GSK1070916 |
分子量 | 507.63 |
分子式 | C30H33N7O |
CAS No. | 942918-07-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 102 mg/mL (200.93 mM)
Ethanol: 8 mg/mL(15.8 mM)
H2O: < 1 mg/mL (insoluble or slightly soluble)
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
GSK-1070916 942918-07-2 Angiogenesis Apoptosis Cell Cycle/Checkpoint Chromatin/Epigenetic PI3K/Akt/mTOR signaling Tyrosine Kinase/Adaptors Tie-2 FLT Aurora Kinase AMPK GSK-1070916A Inhibitor GSK1070916 inhibit GSK 1070916 inhibitor