Powder: -20°C for 3 years | In solvent: -80°C for 1 year
GSK-25 maintains good selectivity against a panel of 31 kinases, as well as RSK1 and p70S6K (RSK1 IC50 of 398 nM, p70S6K IC50 of 1000nM), and a dramatically improved P450 profile (>2.2 uM at all isozymes tested).
説明 | GSK-25 maintains good selectivity against a panel of 31 kinases, as well as RSK1 and p70S6K (RSK1 IC50 of 398 nM, p70S6K IC50 of 1000nM), and a dramatically improved P450 profile (>2.2 uM at all isozymes tested). |
ターゲット&IC50 | mTOR (p70S6K):1000nM, RSK1:398 nM |
別名 | GSK25 |
分子量 | 513.33 |
分子式 | C24H16Cl2F2N6O |
CAS No. | 874119-56-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 60 mg/mL (116.88 mM)
You can also refer to dose conversion for different animals. 詳細
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GSK-25 874119-56-9 Cell Cycle/Checkpoint Cytoskeletal Signaling MAPK PI3K/Akt/mTOR signaling Stem Cells ROCK S6 Kinase mTOR Rho-associated kinase ROK Rho-associated protein kinase S6K bioavailable Ribosomal S6 Kinase (RSK) Rho-kinase Inhibitor p70S6K selective GSK25 pressure P450 inhibit blood orally GSK 25 inhibitor