store at low temperture,keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Go6976 is a small molecule inhibitor of protein kinase C (PKC). Go6976 has been widely used in biomedical research as a tool to study the role of PKC in various physiological and pathophysiological processes.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
無料サンプル 1 mg | |||||
1 mg | 在庫あり | ¥ 18,000 | |||
5 mg | 在庫あり | ¥ 44,000 | |||
10 mg | 在庫あり | ¥ 65,500 | |||
25 mg | 在庫あり | ¥ 111,000 | |||
50 mg | 在庫あり | ¥ 158,000 | |||
100 mg | 在庫あり | ¥ 219,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 45,500 |
説明 | Go6976 is a small molecule inhibitor of protein kinase C (PKC). Go6976 has been widely used in biomedical research as a tool to study the role of PKC in various physiological and pathophysiological processes. |
ターゲット&IC50 | PKCα:2.3 nM, PKC:7.9 nM, PKCβ1:6.2 nM, PKC:20 nM |
In vitro | 30 nM Go6976 is sufficient to cause abrogation of S-phase arrest in 6 h and abrogation of G2 arrest followed by lethal mitosis in 24 h. Incubation of cells with 100 nM Go6976 is sufficient to cause complete abrogation of S and G2 arrest at 6 and 24 h, respectively, which is only slightly less potent than in bovine serum[1]. Go6976 is a potent inhibitor of PKC in vitro (IC50 is 20 nM. This compound is structurally related to staurosporine, which is the most potent PKC inhibitor[2] |
別名 | Gö 6976 |
分子量 | 378.43 |
分子式 | C24H18N4O |
CAS No. | 136194-77-9 |
store at low temperture,keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 45.0 mg/mL (118.9 mM), sonification is recommended.
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Go6976 136194-77-9 Chromatin/Epigenetic Cytoskeletal Signaling PKC Gö 6976 Inhibitor inhibitor inhibit