Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Halofuginone (RU-19110), the competitive inhibitor of prolyl-tRNA synthetase(Ki=18.3 nM), could also down-regulate Smad3 and blocked TGF-β signaling at 10 ng/ml in the mammal.
別名 | Tempostatin, empostatin, RU-19110 |
分子量 | 414.68 |
分子式 | C16H17BrClN3O3 |
CAS No. | 55837-20-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethanol: < 1 mg/mL (insoluble or slightly soluble)
DMSO: 16 mg/mL (38.6 mM)
H2O: < 1 mg/mL (insoluble or slightly soluble)
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Halofuginone 55837-20-2 Cell Cycle/Checkpoint DNA Damage/DNA Repair Membrane transporter/Ion channel Metabolism Microbiology/Virology Stem Cells Sodium Channel DNA/RNA Synthesis Calcium Channel Parasite TGF-beta/Smad osteoarthritis collagen-1 Na+ channels Na channels Transforming growth factor beta prolyl-tRNA Ca2+ channels TGF-β type-I Ca channels inhibit collagen Tempostatin RU19110 empostatin Inhibitor RU 19110 RU-19110 inhibitor