Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Iodophenpropit dihydrobromide is an effective and selective antagonist of the histamine H3 receptor. The binding of [125I]Iodophenpropit is readily reversible, selective, and of high affinity (KD: 0.32 nM).
説明 | Iodophenpropit dihydrobromide is an effective and selective antagonist of the histamine H3 receptor. The binding of [125I]Iodophenpropit is readily reversible, selective, and of high affinity (KD: 0.32 nM). |
ターゲット&IC50 | H3 receptor:0.32 nM (kd) |
In vitro | Iodophenpropit suppresses 5-hydroxytryptamine (5-HT) responses (IC50 of 1.57±0.3 μM)[3]. Iodophenpropit is a very potent H3 receptor antagonist and displays only a moderate affinity for the H1 and H2 receptors [2]. |
In vivo | In rabbits, Iodophenpropit (1 μg/kg; through intramuscular; b.i.d.; for 10 days) displays obviously enhancement of total anti-sheep red blood cells (SRBC)- immunoglobulins (Igs)[4]. |
分子量 | 495.22 |
分子式 | C15H20BrIN4S |
CAS No. | 145196-87-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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Iodophenpropit dihydrobromide 145196-87-8 GPCR/G Protein Immunology/Inflammation Neuroscience Histamine Receptor Iodophenpropit Dihydrobromide Iodophenpropit Inhibitor inhibitor inhibit