Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Irisolidone is a potent volume-regulated anion channel (VRAC) current inhibitor, it exhibits high efficacy for VRAC blockade with IC50s of 5-13 μM.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
無料サンプル 1 mg | |||||
1 mg | 在庫あり | ¥ 28,000 | |||
5 mg | 在庫あり | ¥ 64,000 | |||
10 mg | 在庫あり | ¥ 97,000 | |||
25 mg | 在庫あり | ¥ 158,000 | |||
50 mg | 在庫あり | ¥ 220,000 | |||
100 mg | 在庫あり | ¥ 296,000 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 65,000 |
説明 | Irisolidone is a potent volume-regulated anion channel (VRAC) current inhibitor, it exhibits high efficacy for VRAC blockade with IC50s of 5-13 μM. |
In vivo | Irisolidone may attenuate ethanol-induced gastritis by inhibiting the infiltration of immune cells, particularly neutrophils, through the regulation of CXCL-4 or IL-8 secretion[2]. |
植物由来 |
分子量 | 314.29 |
分子式 | C17H14O6 |
CAS No. | 2345-17-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 3.14 mg/mL (10 mM)
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Irisolidone 2345-17-7 Immunology/Inflammation Membrane transporter/Ion channel NF-Κb Chloride channel IL Receptor NF-κB Chloride Channel Cl? Channels Inhibitor hepatoprotective inhibit VRAC inhibitor