Powder: -20°C for 3 years | In solvent: -80°C for 1 year
JNJ-37822681 is a novel, highly selective dopamine D₂ receptor antagonist characterized by a rapid dissociation rate from the dopamine D₂ receptor.
説明 | JNJ-37822681 is a novel, highly selective dopamine D₂ receptor antagonist characterized by a rapid dissociation rate from the dopamine D₂ receptor. |
ターゲット&IC50 | D2:0.39 mg/kg(ED50) |
In vivo | JNJ-37822681 occupied D2 receptors in rat brain at relatively low doses (ED50 = 0.39 mg/kg) and was effective in animal models of psychosis (e.g., inhibition of apomorphine-induced stereotypy or D-amphetamine/phencyclidine-induced hyperlocomotion)[4]. |
別名 | JNJ37822681, JNJ 37822681 |
分子量 | 372.34 |
分子式 | C17H17F5N4 |
CAS No. | 935776-74-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 55 mg/ml (147.71 mM)
You can also refer to dose conversion for different animals. 詳細
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JNJ-37822681 935776-74-2 GPCR/G Protein Neuroscience Dopamine Receptor JNJ37822681 JNJ 37822681 Inhibitor inhibitor inhibit