Powder: -20°C for 3 years | In solvent: -80°C for 1 year
K 02288 is a novel small molecule inhibitor of ALK1/2/3/6.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
2 mg | 在庫あり | ¥ 7,500 | |||
5 mg | 在庫あり | ¥ 12,000 | |||
10 mg | 在庫あり | ¥ 20,500 | |||
25 mg | 在庫あり | ¥ 38,000 | |||
50 mg | 在庫あり | ¥ 66,500 | |||
100 mg | 在庫あり | ¥ 98,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 13,500 |
説明 | K 02288 is a novel small molecule inhibitor of ALK1/2/3/6. |
ターゲット&IC50 | ALK6:6.4 nM, ALK1:1.8 nM, ALK3:34.4 nM, ALK2:1.1 nM |
In vitro | In zebrafish embryos, K02288 induces dorsal phenotypes in a dose-dependent manner without affecting the formation of intersegmental vessels (ISV). |
In vivo | K02288 dose-dependently inhibits Smad1/5/8 phosphorylation induced by BMP4 and BMP6 in C2C12 cells without affecting TGF-β-BMP signaling. |
別名 | K 02288 |
分子量 | 352.38 |
分子式 | C20H20N2O4 |
CAS No. | 1431985-92-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethanol: 3.5 mg/mL (10 mM)), Heating is recommended.
DMSO: 35.2 mg/mL (100 mM)
You can also refer to dose conversion for different animals. 詳細
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
K02288 1431985-92-0 Angiogenesis Stem Cells Tyrosine Kinase/Adaptors ALK TGF-beta/Smad K-02288 Inhibitor TGF-β Receptor inhibit Transforming growth factor beta receptors K 02288 inhibitor