Kartogenin is an activator of the smad4/smad5 pathway, and promotes the selective differentiation of multipotent mesenchymal stem cells into chondrocytes.
| 説明 | Kartogenin is an activator of the smad4/smad5 pathway, and promotes the selective differentiation of multipotent mesenchymal stem cells into chondrocytes. |
| 細胞研究 | For the cell viability assay, fibroblasts are seeded on six-well plates, followed by Kartogenin or DMSO treatment. According to the manufacturer's instructions, cell viability and viability are assessed by AlamarBlue assay.(Only for Reference) |
| 別名 | KGN |
| 分子量 | 317.34 |
| 分子式 | C20H15NO3 |
| CAS No. | 4727-31-5 |
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
H2O: <1 mg/mL
DMSO: 63 mg/mL (198.52 mM)
Ethanol: 18 mg/mL (56.72 mM), warmed
( < 1 mg/ml refers to the product slightly soluble or insoluble )
参考文献
投与量変換You can also refer to dose conversion for different animals. 詳細
In vivo投与量計算 (透明溶液)計算器bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Kartogenin 4727-31-5 Stem Cells TGF-beta/Smad Inhibitor stem chondrocytes KGN human differentiation inhibit mesenchymal Transforming growth factor beta cells osteoarthritis inhibitor
