LDN-212854, a novel BMP inhibitor, exhibits greater selectivity for BMP versus the TGF-β type I receptors; possesses differences towards ALK2(IC50=1.3 nM) versus ALK1/3 compared to other inhibitors.
| 説明 | LDN-212854, a novel BMP inhibitor, exhibits greater selectivity for BMP versus the TGF-β type I receptors; possesses differences towards ALK2(IC50=1.3 nM) versus ALK1/3 compared to other inhibitors. |
| ターゲット＆IC50 | ALK2:1.3 nM |
| 別名 | LDN212854, BMP Inhibitor III |
| 分子量 | 406.48 |
| 分子式 | C25H22N6 |
| CAS No. | 1432597-26-6 |
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
2eq.HCl: 20.3 mg/mL (50 mM)
( < 1 mg/ml refers to the product slightly soluble or insoluble )
参考文献引用文献
投与量変換You can also refer to dose conversion for different animals. 詳細
In vivo投与量計算 (透明溶液)計算器bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
LDN-212854 1432597-26-6 Angiogenesis Stem Cells Tyrosine Kinase/Adaptors ALK TGF-beta/Smad HCC Huh7 EpCAM Inhibitor BMP LDN212854 LDN 212854 Transforming growth factor beta receptors BMP9-ID1 signaling BMP Inhibitor III MT cell heterotopic ossification FOP model TGF-β Receptor inhibit BMPR2 cell inhibitor
