Powder: -20°C for 3 years | In solvent: -80°C for 1 year
MK2-IN-3 hydrate (MK-2 Inhibitor III) is an orally active, selective, and ATP-competitive inhibitor of MAPKAP-K2 (MK-2) (IC50 of 0.85 nM)
説明 | MK2-IN-3 hydrate (MK-2 Inhibitor III) is an orally active, selective, and ATP-competitive inhibitor of MAPKAP-K2 (MK-2) (IC50 of 0.85 nM) |
ターゲット&IC50 | MK2:0.85 nM, MK3:0.21 μM, MNK1:5.7 μM, ERK2:3.44 μM, MK5:0.081 μM |
In vitro | MK-2 Inhibitor III suppresses TNFα production (IC50 of 4.4 μM, in U397 cells)[1]. |
別名 | MK-2 Inhibitor III |
分子量 | 358.39 |
分子式 | C21H18N4O2 |
CAS No. | 1186648-22-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 65 mg/mL (181.37 mM)
You can also refer to dose conversion for different animals. 詳細
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MK2-IN-3 hydrate 1186648-22-5 MAPK MNK ERK MK-2 Inhibitor III Inhibitor MAP kinase activated protein kinase 2 inhibit MK2 IN 3 hydrate MAPKAP kinase 2 MK-2-IN-3 hydrate MAPK activated protein kinase 2 MK2IN3 hydrate MAPKAPK2 (MK2) MK2-IN-3 Hydrate Mitogen-activated protein kinase activated protein kinase 2 inhibitor