Powder: -20°C for 3 years | In solvent: -80°C for 1 year
ML339 a selective inhibitor of CXCR6(IC50 = 140 nM) with no response when screened against CXCR5 and CXCR4.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 9,000 | |||
5 mg | 在庫あり | ¥ 20,500 | |||
10 mg | 在庫あり | ¥ 34,000 | |||
25 mg | 在庫あり | ¥ 68,500 | |||
50 mg | 在庫あり | ¥ 110,000 | |||
100 mg | 在庫あり | ¥ 158,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 22,500 |
説明 | ML339 a selective inhibitor of CXCR6(IC50 = 140 nM) with no response when screened against CXCR5 and CXCR4. |
ターゲット&IC50 | CXCR6:140 nM |
In vitro | The murine assay was validated using anti-mCXCR16 as an antagonist positive control tested in the presence of an EC80 concentration of mCXCL16 (IC50 = 1.5 nM; % response = 100%). Probe ML339 was shown to be 100-fold less active at the murine CXCR6 receptor using the DiscoveRx β-arrestin cell-based assay format[1]. |
分子量 | 502 |
分子式 | C26H32ClN3O5 |
CAS No. | 2579689-83-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 125 mg/mL (249.00 mM)
You can also refer to dose conversion for different animals. 詳細
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ML339 2579689-83-9 Autophagy GPCR/G Protein Immunology/Inflammation CXCR prostate cancer ML-339 CXC chemokine receptors inhibit CXCR6 2080300-49-6 Inhibitor ML 339 inhibitor