store at low temperature,keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Medicarpin, a legume phytoalexin, acts as an estrogen receptor (ER) agonist, can stimulate osteoblast differentiation likely via ERα2, promote achievement of peak bone mass, and is devoid of uterine estrogenicity; in addition, given its excellent oral bioavailability, it can be potential osteogenic agent.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 36,500 | |||
5 mg | 在庫あり | ¥ 91,000 | |||
10 mg | 在庫あり | ¥ 122,000 | |||
25 mg | 在庫あり | ¥ 197,500 | |||
50 mg | 在庫あり | ¥ 271,000 | |||
100 mg | 在庫あり | ¥ 365,000 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 78,500 |
説明 | Medicarpin, a legume phytoalexin, acts as an estrogen receptor (ER) agonist, can stimulate osteoblast differentiation likely via ERα2, promote achievement of peak bone mass, and is devoid of uterine estrogenicity; in addition, given its excellent oral bioavailability, it can be potential osteogenic agent. |
In vitro | To this aim, 7- and 30-day-old plants were treated with 0, 120, 240, 500, and 1,000 μM Pb during 10 days. The content of Medicarpin was determined by HPLC, and the extent of Medicarpin production was deduced from the result of semiquantitative RT-PCR performed on PAL, CHS, and VR genes. HPLC results indicated that Medicarpin concentration has been reduced in the roots, while its exudation to the culture medium has been increased. RT-PCR results indicated that the transcript levels of PAL, CHS, and VR genes have not been affected following Pb stress in seedlings. At the vegetative stage, transcript levels of PAL and CHS genes have been reduced in the roots. However, the transcript level of VR gene increased at 120 and 240 μM Pb, while it decreased at higher concentrations. In the shoot, the transcript levels of PAL, CHS, and VR genes were increased following increased concentration of lead in the medium[1] |
植物由来 |
分子量 | 270.28 |
分子式 | C16H14O4 |
CAS No. | 32383-76-9 |
store at low temperature,keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 22.5 mg/mL (83.25 mM)
You can also refer to dose conversion for different animals. 詳細
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Medicarpin 32383-76-9 Apoptosis Immunology/Inflammation MAPK JNK ROS BCL inhibit Inhibitor inhibitor