Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Metaproterenol also has anti-inflammatory activity. Metaproterenol is a direct-acting sympathomimetic and a β2-adrenergic receptor (β2AR) agonist (IC50: 68 nM).
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
25 mg | 約6-8 週間 | ¥ 349,000 |
50 mg | 約6-8 週間 | ¥ 454,500 |
100 mg | 約6-8 週間 | ¥ 574,000 |
説明 | Metaproterenol also has anti-inflammatory activity. Metaproterenol is a direct-acting sympathomimetic and a β2-adrenergic receptor (β2AR) agonist (IC50: 68 nM). |
ターゲット&IC50 | β2-adrenoceptor:68 nM |
In vitro | Metaproterenol (10 μM; 74 hours; THP-1 cells and bone marrow macrophages) treatment causes downregulation of NF-κB in high glucose-induced THP-1 cells and bone marrow macrophages. Metaproterenol (10 μM; 74 hours; THP-1 cells and bone marrow macrophages) treatment increases β-arrestin2 and its interaction with IκBα in high glucose-induced THP-1 cells and bone marrow macrophages [1]. |
In vivo | Metaproterenol (Zucker diabetic fatty rats; 12 weeks ) treatment, decreases monocyte activation as well as pro-inflammatory and pro-fibrotic responses in the kidneys and heart. Metaproterenol might have protective effects against diabetic renal and cardiovascular complications[1]. |
別名 | Orciprenaline |
分子量 | 211.26 |
分子式 | C11H17NO3 |
CAS No. | 586-06-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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Metaproterenol 586-06-1 Apoptosis BCL Orciprenaline Inhibitor inhibitor inhibit