Powder: -20°C for 3 years | In solvent: -80°C for 1 year
NRA-0160 is a selective antagonist of dopamine D4 receptor(Ki of 0.48 nM)
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
25 mg | 約6-8 週間 | ¥ 349,000 |
50 mg | 約6-8 週間 | ¥ 454,500 |
100 mg | 約6-8 週間 | ¥ 574,000 |
説明 | NRA-0160 is a selective antagonist of dopamine D4 receptor(Ki of 0.48 nM) |
ターゲット&IC50 | α1-adrenoceptor (rat):237 nM (ki), D4 receptor:0.48 nM (ki), D3 receptor:39 nM (ki), 5-HT2A receptor:180 nM (Ki, in rat) |
In vivo | NRA0160 dose-dependently and significantly reverses the effects of MAP on both A9 and Al0 dopamine neurons.?NRA0160 is slightly more potent in reversiig the effects of MAP on A10 (ED50 = 1.0 mg/kg) than on A9 dopamine neurons (ED50 = 1.3 mg/kg).?NRA0160 reverses the effect of AP0 on both A9 and A10 dopamine neurons.?ED50 values for the effects of NRA0160 on APO-induced inhibition of A9 and A10 dopamine neurons are 1.3 mg/kg and 0.5 mg/kg, respectively[2]. |
分子量 | 439.52 |
分子式 | C24H23F2N3OS |
CAS No. | 204718-47-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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NRA-0160 204718-47-8 GPCR/G Protein Neuroscience Dopamine Receptor NRA 0160 NRA0160 Inhibitor inhibitor inhibit