Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Nitazoxanide (NSC-697855) is a synthetic benzamide with antiprotozoal activity. Nitazoxanide exerts its antiprotozoal activity by interfering with the pyruvate ferredoxin/flavodoxin oxidoreductase dependent electron transfer reaction.
説明 | Nitazoxanide (NSC-697855) is a synthetic benzamide with antiprotozoal activity. Nitazoxanide exerts its antiprotozoal activity by interfering with the pyruvate ferredoxin/flavodoxin oxidoreductase dependent electron transfer reaction. |
ターゲット&IC50 | Influenza virus ranges (canine):0.17-0.21 μM |
In vitro | In a model of abiotic piglet diarrhea, oral administration of Nitazoxanide (250 mg/kg/day) was effective in reducing the survival of parasites within the host organism. |
In vivo | Nitazoxanide effectively inhibits the growth of a broad spectrum of protozoans and helminths, such as Blastocystis hominis, Entamoeba histolytica, and Trichomonas vaginalis, without exhibiting cytotoxicity. It demonstrates inhibitory concentrations against E. histolytica (IC50=0.017 mg/mL, IC90=0.776 mg/mL), G. intestinalis (IC50=0.004 mg/mL, IC90=0.067 mg/mL), and T. vaginalis (IC50= 0.034 mg/mL, IC90=2.046 mg/mL). |
別名 | NSC 697855 |
分子量 | 307.28 |
分子式 | C12H9N3O5S |
CAS No. | 55981-09-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethanol: < 1 mg/mL (insoluble or slightly soluble)
H2O: < 1 mg/mL (insoluble or slightly soluble)
DMSO: 58 mg/mL (188.8 mM)
You can also refer to dose conversion for different animals. 詳細
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Nitazoxanide 55981-09-4 Autophagy Microbiology/Virology Others Influenza Virus Parasite parasitic NSC-697855 helminths protozoa NSC697855 anthelmintic Giardia lamblia NTZ inhibit enteric Inhibitor NSC 697855 bacteria infecting gastroenteritis ,virus trophozoite JEV inhibitor