store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
ONO4057 is a potent and orally active Leukotriene B4 receptor antagonist with an IC50 value of 0.7±0.3 μM. Immunosuppressive effect of ONO4057 on rat allografts.
説明 | ONO4057 is a potent and orally active Leukotriene B4 receptor antagonist with an IC50 value of 0.7±0.3 μM. Immunosuppressive effect of ONO4057 on rat allografts. |
ターゲット&IC50 | LTB4:0.7 μM |
In vivo | The mean animal survivals of ONO4057-treated animals significantly prolong to 21.0±4.4 days compared with 12.0±0.6 days in the control group. Histological findings from grafts taken on day 7 show that severe focal cellular infiltration is observed in both groups, but the degree of hepatocyte necrosis in ONO4057-treated animals is milder than that in the control group[1]. |
別名 | ONO-LB457 |
分子量 | 470.55 |
分子式 | C27H34O7 |
CAS No. | 134578-96-4 |
store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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ONO4057 134578-96-4 GPCR/G Protein Leukotriene Receptor ONO-LB-457 ONO-4057 ONO-LB 457 ONO 4057 ONO-LB457 Inhibitor inhibitor inhibit