Powder: -20°C for 3 years | In solvent: -80°C for 1 year
MI-773 (SAR405838 (MI 773)) is an orally available MDM2 antagonist with Ki of 0.88 nM. Phase 1.
説明 | MI-773 (SAR405838 (MI 773)) is an orally available MDM2 antagonist with Ki of 0.88 nM. Phase 1. |
ターゲット&IC50 | MDM2:0.88 nM(Ki) |
別名 | MI773, MI 773, MI-77301, MI-773 |
分子量 | 562.5 |
分子式 | C29H34Cl2FN3O3 |
CAS No. | 1303607-60-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 93 mg/mL (165.3 mM)
Ethanol: 29 mg/mL (51.6 mM)
H2O: < 1 mg/mL (insoluble or slightly soluble)
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
SAR405838 1303607-60-4 Apoptosis Ubiquitination Mdm2 E1/E2/E3 Enzyme MDM-2/p53 SAR 405838 Ubiquitin activating enzyme MI77301 inhibit MI773 Ubiquitin ligase Inhibitor MI 77301 MI 773 MI-77301 Ubiquitin conjugating enzyme E2 conjugating enzyme SAR-405838 E3 ligating enzyme E1 activating enzyme MI-773 inhibitor