Powder: -20°C for 3 years | In solvent: -80°C for 1 year
SB-218078 is less potently inhibits Cdc2 (IC50: 250 nM) and PKC (IC50: 1000 nM). SB-218078 is a potent, ATP-competitive, and cell-permeable checkpoint kinase 1 inhibitor that inhibits Chk1 phosphorylation of cdc25C (IC50: 15 nM).
説明 | SB-218078 is less potently inhibits Cdc2 (IC50: 250 nM) and PKC (IC50: 1000 nM). SB-218078 is a potent, ATP-competitive, and cell-permeable checkpoint kinase 1 inhibitor that inhibits Chk1 phosphorylation of cdc25C (IC50: 15 nM). |
ターゲット&IC50 | Chk1:15 nM, CDC2:250 nM, PKC:1000 nM, Apoptosis: |
分子量 | 393.39 |
分子式 | C24H15N3O3 |
CAS No. | 135897-06-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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SB-218078 135897-06-2 Cell Cycle/Checkpoint Chromatin/Epigenetic Cytoskeletal Signaling Chk PKC SB218078 SB 218078 Inhibitor inhibitor inhibit