Powder: -20°C for 3 years | In solvent: -80°C for 1 year
XL-413 is an orally bioavailable cell division cycle 7 homolog (CDC7) kinase inhibitor with potential antineoplastic activity. XL-413 binds to and inhibits the activity of CDC7, which may result in the inhibition of DNA replication and mitosis, the induction of tumor cell apoptosis, and the inhibition of tumor cell proliferation in CDC7-overexpressing tumor cells.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 15,000 | |||
5 mg | 在庫あり | ¥ 34,000 | |||
10 mg | 在庫あり | ¥ 47,500 | |||
25 mg | 在庫あり | ¥ 95,000 | |||
50 mg | 在庫あり | ¥ 141,500 | |||
100 mg | 在庫あり | ¥ 201,000 |
説明 | XL-413 is an orally bioavailable cell division cycle 7 homolog (CDC7) kinase inhibitor with potential antineoplastic activity. XL-413 binds to and inhibits the activity of CDC7, which may result in the inhibition of DNA replication and mitosis, the induction of tumor cell apoptosis, and the inhibition of tumor cell proliferation in CDC7-overexpressing tumor cells. |
ターゲット&IC50 | CK2:215nM, Pim1:42 nM, pMCM:118 nM(EC50), CDC7:3.4 nM |
分子量 | 289.72 |
分子式 | C14H12ClN3O2 |
CAS No. | 1169558-38-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: Soluble
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
XL413 1169558-38-6 Cell Cycle/Checkpoint Chromatin/Epigenetic GPCR/G Protein JAK/STAT signaling Metabolism Stem Cells Casein Kinase cholecystokinin Pim CDK inhibit XL-413 Inhibitor Cyclin dependent kinase XL 413 inhibitor