store at low temperature
store at -20°C
Isatuximab is a monoclonal antibody targeting the transmembrane receptor and extracellular enzyme CD38 in malignant cells of the hematological system and is a highly expressed protein in multiple myeloma. Isatuximab has antitumor activity, antibody-dependent cytotoxicity, complement-dependent cytotoxicity, and antibody-dependent cytophagocytosis, which can directly induce apoptosis in the absence of crosslinking. Isatuximab has an inhibitory effect on CD38 extracellular enzyme activity, which is associated with many cellular functions.
説明 | Isatuximab is a monoclonal antibody targeting the transmembrane receptor and extracellular enzyme CD38 in malignant cells of the hematological system and is a highly expressed protein in multiple myeloma. Isatuximab has antitumor activity, antibody-dependent cytotoxicity, complement-dependent cytotoxicity, and antibody-dependent cytophagocytosis, which can directly induce apoptosis in the absence of crosslinking. Isatuximab has an inhibitory effect on CD38 extracellular enzyme activity, which is associated with many cellular functions. |
In vitro | The combination of Isatuximab with Pomalidomide (an immunomodulatory drug) results in greater direct toxicity and lysis of CD38 multiple myeloma cells by effector cells compared with Isatuximab alone [2] . |
別名 | SAR-650984, hu38SB19, Isatuximab-irfc |
分子量 | 145.21 kDa |
CAS No. | 1461640-62-9 |
store at low temperature
store at -20°C
You can also refer to dose conversion for different animals. 詳細
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Isatuximab 1461640-62-9 Apoptosis Immunology/Inflammation CD38 SAR650984 SAR 650984 SAR-650984 hu38SB19 Isatuximab-irfc Inhibitor inhibitor inhibit