ACK

In molecular biology, acetate kinase , which is predominantly found in micro-organisms, facilitates the production of acetyl-CoA by phosphorylating acetate in the presence of ATP and a divalent cation. Short-chain fatty acids (SCFAs) play a major role in carbon cycle and can be utilized as a source of carbon and energy by bacteria.

Cat. No.	製品名	CAS No.	Purity
T2641	KRCA-0008	1472795-20-2	98%
T2641	KRCA-0008 is an effective and specific ALK/Ack1 inhibitor (IC50: 12/4 nM); displays drug-like properties without hERG liability.
T3196	GNF-7	839706-07-9	97.05%
T3196	GNF-7 is Bcr-Abl WT and Bcr-Abl T315I inhibitor with IC50 of 133 nM and 61 nM, respectively.
T13564	AZ7550	1421373-99-0	97.07%
T13564	AZ7550, an active metabolite of AZD9291, inhibits the activity of IGF1R (IC50: 1.6 μM).
T5092	AIM-100	873305-35-2	98.75%
T5092	AIM-100 is a Ack1 inhibitor (IC50: 24 nM).
T2382	Vemurafenib	918504-65-1	99.65%
T2382	Vemurafenib (RG7204) is a B-RAF inhibitor that inhibits RAFV600E and c-RAF-1 (IC50=31/48 nM) selectively and potently. Vemurafenib exhibits antitumor activity an...