AChR

α-Conotoxin PIA acetate is an antagonist of nicotinic acetylcholine receptor (nAChR) mainly targeting α6 and α3 subunits.

YM17E is an inhibitor of ACAT with IC50 of 44 nM in rabbit liver microsomes in vitro.

Fmoc-Val-Ala-PAB-OH (Fmoc-Val-Ala-PAB) is a useful linker for making Antibody-Drug-Conjugation (ADC) conjugate for targeting drug delivery. It is also utilized i...

Dimethindene (Dimetindeno) is a selective antagonist of H1 receptor and blocks K+ current. Dimethindene exhibits antihistamine and anticholinergic effects.

Tribendimidine is a broad-spectrum, orally active anthelmintic and an L-type nicotinic acetylcholine receptor (nAChR) agonist. tribendimidine is highly active ag...

VU0453595 is a M1 positive allosteric modulator (PAM).

muscarinic M1 antagonist

Garcinone C is a xanthone derivative extracted from Garcinia oblongifolia Champ with anti-inflammatory, astringency, and granulation-promoting activities. Garcin...

Zamifenacin fumarate (UK-76654 fumarate) is a potent and gut-selective antagonist of muscarinic M3 receptor.

Mc-Val-Ala-PAB, an effective linker, is utilized in antibody-drug-conjugate (ADC).

Isoxazole (1,2-oxazole) is the inhibitor of acetylcholinesterase (AChE). The ligands of Isoxazole bind to and inhibit the Sxc- antiporter.

Facinicline hydrochloride (RG3487) is both a novel nicotinic alpha-7 receptor (alpha7nAChR) partial agonist (Ki = 6 nM) and an antagonist of 5-HT3(Ki = 1.2 nM). ...

5-AAM-2-CP is one of the major metabolites of Acetamiprid. Acetamiprid, a nAChR agonist, is a neonicotinoid insecticide used worldwide.

CB-7921220 (6-[2-(4-Aminophenyl)vinyl]-2-pyridinecarboxylic acid) is an inhibitor of adenylate cyclase.

8-Aminoadenine (7H-purine-6,8-diamine) is a ligand for Adenine Receptor with Ki of 0.0341 μM.

(-)-Coclaurine hydrochloride is an antagonist of nAChRs isolated from Sarcopetalum harveyanum.

Minaprine is a reversible inhibitor of MAO-A, used in the treatment of various depressive states.

Methscopolamine (Hyoscine methyl bromide) (Pamine), as a natural plant alkaloid, is a muscarinic acetylcholine receptor blocker.

Tropicamide (Ro 1-7683) is a synthetic muscarinic antagonist with actions similar to atropine and with an anticholinergic property. Upon ocular administration, t...

Thiacloprid is a neonicotinoid insecticide that acts as a selective agonist at insect nicotinic acetylcholine receptors (nAChRs) with IC50values of 2.7 and 860 n...