| T10503 |
ACAT-IN-1 cis isomer
|
145961-79-1
|
98%
|
|
|
ACAT-IN-1 cis isomer is a potent ACAT inhibitor (IC50: 100 nM) for the study of immune system-related diseases.
|
| T13373 |
YM17E
|
124900-72-7
|
98%
|
|
|
YM17E is an inhibitor of ACAT with IC50 of 44 nM in rabbit liver microsomes in vitro.
|
| T4681 |
T863
|
701232-20-4
|
98%
|
|
|
T-863(DGAT-1 inhibitor) is an orally active, selective and potent DGAT1 (Acyl-CoA:diacylglycerol acyltransferase 1) inhibitor that interacts with the acyl-CoA bi...
|
| T5544 |
2-Furoic acid
|
88-14-2
|
98%
|
|
|
2-Furoic acid (Furan-2-carboxylic acid) 2-Furoic acid can reduce serum cholesterol and triglyceride levels and has anti-lipidemic effects.
|
| T6365 |
A 922500
|
959122-11-3
|
98%
|
|
|
A 922500 (DGAT-1 Inhibitor 4a) is an inhibitor for human and mouse DGAT-1 with IC50 of 7 nM and 24 nM, respectively, good selectivity over related acyltransferas...
|
| T14523 |
Beauvericin
|
26048-05-5
|
98%
|
|
|
Beauvericin, a Fusarium mycotoxin, inhibits acyl-CoA:cholesterol acyltransferase (ACAT) in rat liver microsomal enzyme assays with an IC50 value of 3 μM.
|
| T23521 |
VULM 1457
|
228544-65-8
|
98%
|
|
|
VULM 1457 is a potent ACAT inhibitor. VULM 1457 has remarkable hypolipidaemic activity and improves the overall myocardial ischaemia-reperfusion injury outcomes....
|
| T11733 |
K-604 dihydrochloride
|
217094-32-1
|
98%
|
|
|
K-604 dihydrochloride is a potent and selective acyl-CoA:cholesterol acyltransferase 1 inhibitor with an IC50 of 0.45±0.06 μM.
|
| T10035 |
10,12-Tricosadiynoic acid
|
66990-30-5
|
|
|
|
10,12-Tricosadiynoic acid is a highly selective and orally active inhibitor of acyl-CoA oxidase-1 (ACOX1). It can treat the high-fat diet- or obesity-induced met...
|
| T73350 |
BAY-3827
|
2377576-35-5
|
100%
|
|
|
BAY-3827 is a potent and selective AMPK inhibitor with potential antitumor activity, showing antiproliferative activity in an androgen-dependent prostate cancer ...
|
| T0504 |
Cyclandelate
|
456-59-7
|
98%
|
|
|
Cyclandelate (BS 572), a direct-acting smooth muscle relaxant, is used to dilate blood vessels.
|
| T1519L |
Rimonabant
|
168273-06-1
|
98%
|
|
|
Rimonabant (SR141716) is an inverse agonist for the cannabinoid receptor CB1. It is an anorectic anti-obesity drug produced and marketed by Sanofi-Aventis. Its m...
|
| T8236 |
RHC 80267
|
83654-05-1
|
98%
|
|
|
RHC 80267 (U-57908) is a selective inhibitor of DAGL (IC50 : 4 μM in canine platelets)
|
| T31611 |
Eldacimibe
|
141993-70-6
|
98.30%
|
|
|
Eldacimibe (WAY-ACA-147) is an ACAT2 inhibitor for the treatment of cardiovascular disease and endocrine and metabolic disorders, study of atherosclerosis and hy...
|
| T27245L |
Eflucimibe
|
202340-45-2
|
98.56%
|
|
|
Eflucimibe (L0081) is an acyl coenzyme A: cholesterol acyltransferase inhibitor for the treatment of cardiovascular disease and endocrine and metabolic disorders...
|
| T2753 |
Avasimibe
|
166518-60-1
|
98.77%
|
|
|
Avasimibe (PD-148515) is an orally bioavailable inhibitor of acyl-Coenzyme A: cholesterol acyltransferase (ACAT, IC50: 3.3 μM) that prevents cholesterol depositi...
|
| T12767 |
RP 70676
|
136609-26-2
|
98.89%
|
|
|
RP 70676 is a potent ACAT inhibitor(rat and rabbit ACAT with IC50 of 25 and 44 nM ).
|
| T8314 |
RP-64477
|
135239-65-5
|
99.16%
|
|
|
RP-64477 is the cholesterol esterifying enzyme Acyl-coenzyme A:cholesterol O-acyltransferase (ACAT) inhibitor.
|
| T3342 |
Xanthohumol
|
6754-58-1
|
99.18%
|
|
|
Xanthohumol, also known as 2', 4, 4'-trihydroxy-6'-methoxy-3'-prenylchalcone or desmethylxanthohumol, is a member of the class of compounds known as 3-prenylated...
|
| T25635 |
Lateritin
|
65454-13-9
|
99.23%
|
|
|
Lateritin (Bassiatin) is An Acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor and a platelet aggregation inhibitor from the mycelial cake of Gibberella later...
|
