| T4608 |
PDM2
|
688348-25-6
|
98%
|
|
|
PDM 2 is a potent and selective aryl hydrocarbon receptor (AhR) antagonist.
|
| T20625 |
Prochloraz
|
67747-09-5
|
98%
|
|
|
Prochloraz (Prelude) is a broad-spectrum contact imidazole fungicide. Prochloraz inhibits human placental microsomal aromatase in vitro (IC50 = 40 nM). Prochlora...
|
| T4607 |
CAY 10465
|
688348-33-6
|
98%
|
|
|
CAY 10465 is a selective and high-affinity AhR agonist, with a Ki of 0.2 nM, and shows no effect on estrogen receptor (Ki >100000 nM).
|
| T4644 |
Tapinarof
|
79338-84-4
|
98%
|
|
|
Tapinarof (Benvitimod) is targeted as a topical cream treatment for psoriasis, a chronic autoimmune skin disease.
|
| TN1451 |
Brevifolincarboxylic acid
|
18490-95-4
|
98%
|
|
|
Brevifolincarboxylic acid is a natural product isolated from Polygonum capitatum, it has inhibitory effect on the aryl hydrocarbon receptor (AhR). Brevifolincarb...
|
| T23151 |
Phortress
|
328087-38-3
|
100%
|
|
|
Phortress (NSC-710305) is a potent AhR ligand with strong binding affinity, which subsequently triggers the transcription of CYP1A1 and induces antitumor activit...
|
| T10938 |
D-Kynurenine
|
13441-51-5
|
97.08%
|
|
|
D-Kynurenine (ZINC901103) is a metabolite of D-tryptophan and an agonist of GPR109B. D-Kynurenine activates AhR and promotes the conversion of the epithelium to ...
|
| T7202 |
ITE
|
448906-42-1
|
98%
|
|
|
ITE is a potent endogenous agonist of aryl hydrocarbon receptor (AhR) (Ki : 3 nM), has immunosuppressive activity.
|
| T5622 |
BAY-218
|
2162982-11-6
|
98%
|
|
|
BAY-218 (AHR antagonist 1) is an aryl hydrocarbon receptor (AHR) antagonist , has an IC50 of 39.9 nM in human cell line.
|
| T1960 |
YL-109
|
36341-25-0
|
98%
|
|
|
YL-109, a novel anticancer agent, can inhibit breast Y cell growth and invasiveness in vitro and in vivo.
|
| T1046 |
Mexiletine hydrochloride
|
5370-01-4
|
98.44%
|
|
|
Mexiletine hydrochloride (KOE-1173 hydrochloride) is a voltage-gated sodium channel blocker and a Class IB antiarrhythmic drug. Mexiletine hydrochloride exerts a...
|
| T2448 |
CH-223191
|
301326-22-7
|
99.01%
|
|
|
CH-223191 is a potent and specific antagonist for aryl hydrocarbon receptor (AhR).
|
| T0343 |
Nimodipine
|
66085-59-4
|
99.56%
|
|
|
Nimodipine (BAY-e 9736), a 1, 4-dihydropyridine calcium channel blocker, acts primarily on vascular smooth muscle cells.
|
| T9822 |
WAY-605471
|
378223-81-5
|
99.57%
|
|
|
WAY-605471 is a AHR antagonist with IC50 of 0.5 - 1 μM.
|
| T1159 |
Leflunomide
|
75706-12-6
|
99.6%
|
|
|
Leflunomide (HWA486) is an immunomodulatory agent used in the therapy of rheumatoid arthritis and psoriatic arthritis.
|
| T10007 |
1,4-Chrysenequinone
|
100900-16-1
|
99.65%
|
|
|
1,4-Chrysenequinone (Chrysene-1,4-dione) is an activator of aryl hydrocarbon receptor (AhR).
|
| T1831 |
StemRegenin 1
|
1227633-49-9
|
99.66%
|
|
|
StemRegenin 1 (SR1) is an aryl hydrocarbon receptor (AhR) inhibitor.
|
| T5281 |
Skatole
|
83-34-1
|
99.74%
|
|
|
Skatole (3-Methyl-1H-indole) is produced by intestinal bacteria. Skatole regulates intestinal epithelial cellular functions through activating aryl hydrocarbon r...
|
| T5541 |
PDM11
|
1032508-03-4
|
99.77%
|
|
|
PDM11 (1-[2-(4-Chloro-phenyl)-vinyl]-3,5-diMeth) is an antagonist of aryl hydrocarbon receptor (AhR)
|
| T4938 |
Potassium 1H-indol-3-yl sulfate
|
2642-37-7
|
99.87%
|
|
|
Potassium 1H-indol-3-yl sulfate (Potassium 3-indoxyl sulfate) is an agonist for the human Aryl Hydrocarbon Receptor (AhR). The Aryl Hydrocarbon Receptor (AhR) ha...
|
