| T76766 |
Mirvetuximab
|
1453084-36-0
|
98%
|
Mirvetuximab
|
|
Mirvetuximab (M9346A) is a novel monoclonal antibody targeting anti-FOLR1 (folate receptor 1) with folate receptor α (FRα). Mirvetuximab soravtansine is often co...
|
| T76720 |
Farletuzumab
|
896723-44-7
|
98%
|
Farletuzumab
|
|
Farletuzumab (MORAb-003) is a potent inhibitor of folate receptor-α (FRα). Farletuzumab is a humanized monoclonal antibody with a high affinity for FRα. Farletuz...
|
| T6120 |
Pralatrexate
|
146464-95-1
|
98%
|
|
|
Pralatrexate (10-Propargyl-10-deazaaminopterin) is a folate analogue inhibitor of dihydrofolate reductase (DHFR) exhibiting high affinity for reduced folate carr...
|
| T7598 |
Calcium N5-methyltetrahydrofolate
|
26560-38-3
|
98%
|
|
|
Calcium N5-methyltetrahydrofolate (NSC-173328) is the calcium salt of levomefolic acid, which has been proposed for treatment of cardiovascular disease and advan...
|
| T0189 |
Pemetrexed
|
137281-23-3
|
100%
|
|
|
Pemetrexed (LY-231514 Disodium Hydrate), a guanine-derived antineoplastic agent, binds to and inhibits the enzyme thymidylate synthase (TS).
|
| T0148L |
Folinic Acid Calcium Salt Pentahydrate
|
6035-45-6
|
100%
|
|
|
Folinic Acid Calcium Salt Pentahydrate (Leucovorin Calcium Pentahydrate), a reduced folic acid, is used in combination with other chemotherapeutics.
|
| T16045 |
Methotrexate metabolite
|
19741-14-1
|
95.28%
|
|
|
Methotrexate metabolite (DAMPA) (DAMPA) is the active metabolite of Methotrexate. Methotrexate is a folic acid antagonist. Methotrexate is used as a chemotherape...
|
| T7593 |
Levomefolate calcium
|
151533-22-1
|
98%
|
|
|
Levomefolate calcium is an artificial form of folate. It is a coenzymated form of folic acid and a more bioavailable alternative in dietary supplements.
|
| T7730 |
Aminopterin
|
54-62-6
|
98%
|
|
|
Aminopterin (4-Aminofolic acid) is a synthetic folic acid derivative whose metabolite is a competitive inhibitor of dihydrofolate reductase
|
| T4382 |
Proguanil hydrochloride
|
637-32-1
|
98.13%
|
|
|
Proguanil hydrochloride (Chloroquanil) is a biguanide compound which metabolizes in the body to form cycloguanil, an anti-malaria agent.Upon hydrolysis, Proguani...
|
| T6431 |
Levoleucovorin Calcium
|
80433-71-2
|
98.46%
|
|
|
Levoleucovorin Calcium (CL307782), a calcium salt of the folinic acid, is used in cancer chemotherapy as an adjuvant.
|
| T8548 |
Metoprine
|
7761-45-7
|
99.09%
|
|
|
Metoprine is a potent inhibitor of histamine N-methyltransferase (HMT), with potential antineoplastic activity.
|
| T6226 |
Pemetrexed disodium hemipenta hydrate
|
357166-30-4
|
99.16%
|
|
|
Pemetrexed disodium hemipenta hydrate (LY-231514 Disodium Hydrate) is a new-type antifolate and antimetabolite for TS, DHFR, and GARFT. The Ki of Pemetrexed Diso...
|
| T2204 |
Diaveridine
|
5355-16-8
|
99.19%
|
|
|
Diaveridine (AI3-23935) (DVD) is a popular antibacterial synergist that is widely used in combination with sulfonamide. It has been reported to be genotoxic to m...
|
| T0148 |
Folinic acid calcium
|
1492-18-8
|
99.3%
|
|
|
Folinic acid calcium (Leucovorin Calcium) is the active metabolite of folic acid. Leucovorin is used principally as an antidote to folic acid antagonists.
|
| T1485 |
Methotrexate
|
59-05-2
|
99.46%
|
|
|
Methotrexate (WR19039) is a folate analog, an inhibitor of the dihydrofolate reductase DHFR. Methotrexate has antimetabolic, antitumor, and immunosuppressive act...
|
| T24403 |
Folinic acid
|
58-05-9
|
99.7%
|
|
|
Folinic acid (Leucovorin) is a biofolic acid that can be used in the treatment of methotrexate, often in combination with Methotrexate (MTX) to reduce MTX-induce...
|
| T0849 |
Pyrimethamine
|
58-14-0
|
99.74%
|
|
|
Pyrimethamine (Pirimecidan) is a competitive inhibitor of dihydrofolate reductase (DHFR), used as an antimalarial drug.
|
| T8003 |
Methotrexate disodium
|
7413-34-5
|
99.77%
|
|
|
Methotrexate disodium is an tetrahydrofolate dehydrogenase inhibitor
|
| T1153 |
Trimethoprim
|
738-70-5
|
99.81%
|
|
|
Trimethoprim (NSC-106568) is a Dihydrofolate Reductase Inhibitor Antibacterial. The mechanism of action of trimethoprim is as a Dihydrofolate Reductase Inhibitor...
|
