| T6892 |
Niraparib tosylate
|
1038915-73-9
|
98%
|
|
|
Niraparib tosylate (MK-4827 (tosylate))(with IC50 of 3.8 nM/2.1 nM) is a selective PARP1/PARP2 inhibitor.
|
| T6893 |
MK-886
|
118414-82-7
|
98%
|
|
|
MK-886 (L 663536) is an inhibitor of leukotriene biosynthesis, inhibiting 5-lipoxygenase-activating protein (FLAP). It is also a moderately potent PPARα antagoni...
|
| T4123 |
LYN-1604
|
2088939-99-3
|
98%
|
|
|
LYN-1604 is a novel activator of ULK1, inducing cell death involved in ATF3, RAD21, and caspase3, accompanied by autophagy and apoptosis.
|
| T2982 |
Xanthone
|
90-47-1
|
98%
|
|
|
Xanthone (Xanthenone) is currently used as ovicide for codling moth eggs and as a larvicide.
|
| T3105 |
PFK-158
|
1462249-75-7
|
98%
|
|
|
PFK-158 is an effective and specific inhibitor PFKFB3.
|
| T2S1008 |
Oxysophoridine
|
54809-74-4
|
98%
|
|
|
Oxysophoridine (Sophoridine N-oxide) has a protective effect on focal cerebral ischemic injury through antioxidant and anti-apoptotic mechanisms; it may be a pot...
|
| T14298 |
Rimiducid
|
195514-63-7
|
98%
|
|
|
Rimiducid is a lipid-permeable tacrolimus analogue, homodimerizing an analogue of human protein fkbp12 and binding to wild-type fkbp12 with 1000-fold lower affin...
|
| T6629 |
PYR-41
|
418805-02-4
|
98%
|
|
|
PYR-41 is the first cell-permeable inhibitor of ubiquitin-activating enzyme E1, with no activity at E2.
|
| T6309 |
AZ960
|
905586-69-8
|
98%
|
|
|
AZ960 is an effective ATP competitive JAK2 inhibitor (IC50/Ki: <3 nM and0.45 nM).
|
| T4230 |
PF-3758309 hydrochloride
|
1279034-84-2
|
98%
|
|
|
PF-3758309 hydrochloride (PF-03758309 hydrochloride) , is a PAK4 inhibitor, is also a n orally bioavailable small-molecule inhibitor of p21-activated kinase 4 (P...
|
| T4263 |
BAY 61-3606
|
732983-37-8
|
98%
|
|
|
BAY 61-3606 (Syk inhibitor IV) is a potent, ATP-competitive, reversible, and highly selective inhibitor of Syk tyrosine kinase activity (Ki= 7.5 nM), exhibiting ...
|
| T25212 |
CCCI-01
|
215778-97-5
|
98%
|
|
|
CCCI-01（Centrosome Clustering Chemical Inhibitor-01） is a centrosome cluster inhibitor. CCCI-01 has anticancer activity, induces apoptosis, and can be used in th...
|
| T3010 |
Xanthurenic Acid
|
59-00-7
|
98%
|
|
|
Xanthurenic Acid (8-Hydroxykynurenic acid), a molecule arising from tryptophan metabolism by transamination of 3-hydroxykynurenine, activates mGlu2/3 Metabotropi...
|
| T6085 |
PF-543
|
1415562-82-1
|
98%
|
|
|
PF-543 (Sphingosine Kinase 1 Inhibitor II), a novel sphingosine-competitive inhibitor of SphK1, inhibits SphK1 with IC50 and Ki of 2.0 nM and 3.6 nM.
|
| T5939 |
Calcium dobesilate
|
20123-80-2
|
98%
|
|
|
Calcium dobesilate(CaD) has angioprotective properties and protects endothelial cells partly by ameliorating HG induced inflammation.
|
| T8464 |
RA-9
|
919091-63-7
|
98%
|
|
|
RA-9 is a potent and selective proteasome-associated inhibitor of deubiquitinating enzymes (DUBs), with favorable toxicity profile and anticancer activity. RA-9 ...
|
| T6470 |
Diclofenac Potassium
|
15307-81-0
|
98%
|
|
|
Diclofenac Potassium (CGP-45840B) is a nonsteroidal anti-inflammatory drug taken to reduce inflammation and as an analgesic reducing pain in certain conditions.
|
| T35610 |
2,5-dimethyl Celecoxib
|
457639-26-8
|
98%
|
|
|
2,5-dimethyl Celecoxib is a derivative of celecoxib that does not inhibit COX-2 (IC50 = >100 μM).1 It does inhibit microsomal prostaglandin E synthase-1 (mPGES-1...
|
| T6207 |
SC144
|
895158-95-9
|
98%
|
|
|
SC144 is an orally active small-molecule gp130 inhibitor.
|
| T0093 |
Sorafenib tosylate
|
475207-59-1
|
98%
|
|
|
Sorafenib tosylate (Bay 43-9006) is a potent multikinase inhibitor (IC50s: 6/20/22 nM for Raf-1/VEGFR-3/B-Raf).
|
