| T4608 |
PDM2
|
688348-25-6
|
98%
|
|
|
PDM 2 is a potent and selective aryl hydrocarbon receptor (AhR) antagonist.
|
| T13276 |
VAF347
|
574759-62-9
|
98%
|
|
|
VAF347 is a cell-permeable and highly affinity agonist of the aryl hydrocarbon receptor (AhR) with anti-inflammatory effects.
|
| T6795 |
Carbidopa
|
28860-95-9
|
|
|
|
Carbidopa (Lodosyn) is an aromatic-L-amino-acid decarboxylase inhibitor (IC50: 29±2 μM). It is used in PARKINSON DISEASE to reduce peripheral adverse effects of ...
|
| T4607 |
CAY 10465
|
688348-33-6
|
|
|
|
CAY 10465 is a selective and high-affinity AhR agonist, with a Ki of 0.2 nM, and shows no effect on estrogen receptor (Ki >100000 nM).
|
| T4644 |
Tapinarof
|
79338-84-4
|
|
|
|
Tapinarof (Benvitimod) is targeted as a topical cream treatment for psoriasis, a chronic autoimmune skin disease.
|
| T2148 |
Carbidopa monohydrate
|
38821-49-7
|
|
|
|
Carbidopa monohydrate (S(-)-Carbidopa) is an inhibitor of DOPA decarboxylase, preventing the conversion of levodopa to dopamine.
|
| T2947 |
Indole-3-carbinol
|
700-06-1
|
100%
|
|
|
Indole-3-carbinol (I3C), a naturally occurring, orally available cleavage product of the glucosinolate glucobrassicanin, inhibits NF-κB and IκBα kinase activatio...
|
| T7202 |
ITE
|
448906-42-1
|
98%
|
|
|
ITE is a potent endogenous agonist of aryl hydrocarbon receptor (AhR) (Ki : 3 nM), has immunosuppressive activity.
|
| T1960 |
YL-109
|
36341-25-0
|
98%
|
|
|
YL-109, a novel anticancer agent, can inhibit breast Y cell growth and invasiveness in vitro and in vivo.
|
| TQ0257 |
FICZ
|
172922-91-7
|
98.00%
|
|
|
FICZ (6-Formylindolo[3,2-b]carbazole) is a potent aryl agonist for the hydrocarbon receptor (AhR, Kd: 70 pM).
|
| T0878 |
Diosmin
|
520-27-4
|
98.14%
|
|
|
Diosmin (Venosmine) is a bioflavonoid that strengthens vascular walls.
|
| T2623 |
PD98059
|
167869-21-8
|
98.52%
|
|
|
PD98059 is an MEK inhibitor that inhibits MEK1 and MEK2 (IC50=2/50 μM) and is non-ATP-competitive. PD98059 is also antagonistic as a ligand for AHR. PD98059 inhi...
|
| T2707 |
Pifithrin-α hydrobromide
|
63208-82-2
|
98.54%
|
|
|
Pifithrin-α hydrobromide (Pifithrin-α hydrobromide) is a p53 inhibitor, inhibiting p53-dependent transactivation of p53-responsive genes.
|
| T21966 |
MeBIO
|
667463-95-8
|
98.84%
|
|
|
MeBIO is an agonist of aryl hydrocarbon receptor, with IC50 of 44 and 55 μM for GSK-3 and CDK1/CyclinB, respectively. MeBIO does not affect GSK-3β.
|
| T2448 |
CH-223191
|
301326-22-7
|
99.01%
|
|
|
CH-223191 is a potent and specific antagonist for aryl hydrocarbon receptor (AhR).
|
| T15410 |
GNF351
|
1227634-69-6
|
99.04%
|
|
|
GNF351 is a full antagonist of the aryl hydrocarbon receptor (AHR)with the capacity to inhibit both DRE-dependent and -independent activity. GNF351 is minimal to...
|
| T10269 |
AHR antagonist 2
|
2338747-54-7
|
99.12%
|
|
|
AHR antagonist 2 is an antagonist of the aryl hydrocarbon receptor. The IC50s for human AHR and mouse AHR are 0.885 and 2.03 nM, respectively.
|
| T39762 |
AHR antagonist 5 free base
|
2247950-42-9
|
99.29%
|
|
|
AHR antagonist 5 free base is an orally active antagonist of AHR with IC50s of ~35-150 nM in human and rodent cell lines.
|
| TN1451 |
Brevifolincarboxylic acid
|
18490-95-4
|
99.42%
|
|
|
Brevifolincarboxylic acid is a natural product isolated from Polygonum capitatum, it has inhibitory effect on the aryl hydrocarbon receptor (AhR). Brevifolincarb...
|
| T1831 |
StemRegenin 1
|
1227633-49-9
|
99.66%
|
|
|
StemRegenin 1 (SR1) is an aryl hydrocarbon receptor (AhR) inhibitor.
|
