T4123 |
LYN-1604
|
2088939-99-3
|
98%
|
|
LYN-1604 is a novel activator of ULK1, inducing cell death involved in ATF3, RAD21, and caspase3, accompanied by autophagy and apoptosis.
|
T0293 |
Metyrapone
|
54-36-4
|
98%
|
|
Metyrapone (NSC-25265) is an inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the ...
|
T0957 |
Isradipine
|
75695-93-1
|
98%
|
|
Isradipine (PN 200-110) is a dihydropyridine calcium channel blockers with antihypertensive and vasodilator activities. Isradipine blocks the calcium entry throu...
|
T6010 |
Idarubicin hydrochloride
|
57852-57-0
|
98%
|
|
Idarubicin hydrochloride (Zavedos), a hydrochloride salt form of Idarubicin, is a DNA topoisomerase II (topo II) inhibitor for MCF-7 cells ( IC50: 3.3 ng/mL).
|
T3105 |
PFK-158
|
1462249-75-7
|
98%
|
|
PFK-158 is an effective and specific inhibitor PFKFB3.
|
T64755 |
Ammonium Chloride
|
12125-02-9
|
98%
|
|
Ammonium chloride acts as a small molecule autophagy inhibitor.Ammonium chloride is a pH-regulating, heteropolar compound that can cause intracellular alkalosis ...
|
TN1507 |
Clematichinenoside AR
|
761425-93-8
|
98%
|
|
Clematichinenoside AR exerts anti-inflammatory and immunosuppressive properties, it has anti-arthritic effects on PI3K/Akt signaling pathway and TNF-α± associate...
|
T7697 |
BIX-01294
|
935693-62-2
|
98%
|
|
BIX-01294 is an G9a Histone Methyltransferase inhibitor(IC50 : 1.9 μM).
|
T6085 |
PF-543
|
1415562-82-1
|
98%
|
|
PF-543 (Sphingosine Kinase 1 Inhibitor II), a novel sphingosine-competitive inhibitor of SphK1, inhibits SphK1 with IC50 and Ki of 2.0 nM and 3.6 nM.
|
T6344 |
Sevelamer hydrochloride
|
152751-57-0
|
98%
|
|
Sevelamer hydrochloride (Sevelamer HCl) is a phosphate binding drug used to treat hyperphosphatemia via binding to dietary phosphate and prevents its absorption....
|
T6283 |
Wortmannin
|
19545-26-7
|
98%
|
|
Wortmannin (SL-2052) is the first described PI3K inhibitor with IC50 of 3 nM, with little selectivity within the PI3K family. Also blocks autophagosome formation...
|
T1920 |
Capivasertib
|
1143532-39-1
|
98%
|
|
Capivasertib (AZD5363) (AZD5363) is a new-type orally available inhibitor of the serine/threonine protein kinase AKT (IC50s: 3/7/7 nM for Akt1/2/3).
|
T6057 |
URMC-099
|
1229582-33-5
|
98%
|
|
URMC-099 is an orally bioavailable, brain penetrant MLK inhibitor (IC50: 19/42/14/150 nM, for MLK1/MLK2/MLK3/DLK), and also inhibits LRRK2 activity (IC50: 11 nM)...
|
T0093 |
Sorafenib tosylate
|
475207-59-1
|
98%
|
|
Sorafenib tosylate (Bay 43-9006) is a potent multikinase inhibitor (IC50s: 6/20/22 nM for Raf-1/VEGFR-3/B-Raf).
|
TN1141 |
Isodeoxyelephantopin
|
38927-54-7
|
98%
|
|
Isodeoxyelephantopin exerts antitumor effects on several cancer cells by inducing apoptosis , cell cycle arrest , and inhibiting proliferation. It enhances apopt...
|
T67914 |
Insecticidal agent 364
|
556055-08-4
|
98%
|
|
Insecticidal agent 364 is a selective small molecule inhibitor of rapamycin kinase target protein. Insecticidal agent 364 has antitumor activity, and by inhibiti...
|
T18987 |
Py-BODIPY-NHS ester
|
201998-61-0
|
98%
|
|
Py-BODIPY-NHS ester is a small molecular dye with strong UV absorption that can be used to label living cells and immobilise cells.
|
T60967 |
Atg4B-IN-2
|
2765008-88-4
|
98%
|
|
Atg4B-IN-2 is a potent and selective Atg4B inhibitor with anticancer activity that inhibits the activity of Atg4B and PLA2.Atg4B-IN-2 resists the anticancer acti...
|
T6899 |
MRT68921
|
1190379-70-4
|
98%
|
|
MRT68921 is a potent and dual autophagy kinase ULK1/2 inhibitor with IC50 of 2.9 nM and 1.1 nM, respectively.
|
T2399 |
Bortezomib
|
179324-69-7
|
98%
|
|
Bortezomib (LDP 341) is a 20S proteasome inhibitor (Ki=0.6 nM) that is reversible and selective. Bortezomib has antitumor activity and inhibits NF-κB, which can ...
|