| T6275 |
Obatoclax Mesylate
|
803712-79-0
|
99.38%
|
|
|
Obatoclax Mesylate (GX15-070) is a Bcl-2 antagonist (Ki: 0.22 μM) and can induce apoptosis with up-regulation of Bim, induced cytochrome c release, and activatio...
|
| T17247 |
VU0661013
|
2131184-57-9
|
99.46%
|
|
|
VU0661013 is an effective and selective inhibitor of MCL-1.
|
| T7727 |
Se-Methylselenocysteine
|
26046-90-2
|
99.49%
|
|
|
Se-Methylselenocysteine (Se-MSC) is a potent chemopreventive agent in many test systems and has been shown to inhibit tumor promotion and induce apoptosis.
|
| T5210 |
BAI1
|
335165-68-9
|
99.58%
|
|
|
BAI1 (Bax channel blocker) is a potent inhibitor of Bax-mediated mitochondrial cytochrome C release (IC50: 0.52 μM).
|
| T3867 |
Alpinetin
|
36052-37-6
|
99.61%
|
|
|
Alpinetin ((-)-alpinetin) has antibacterial activity.Alpinetin has anti-inflammatory activity.Alpinetin can enhance the sensitivity of HepG2 hepatoma cells to th...
|
| T9113 |
Myristicin
|
607-91-0
|
99.63%
|
|
|
Myristicin (Myristicine) is a natural product found in spices and umbelliferous plants. Myristicin has anti-cholinergic, Antibacterial, and hepatoprotective effe...
|
| T14376 |
AZD4320
|
1357576-48-7
|
99.71%
|
|
|
AZD4320 is an inhibitor of BH3-mimicking dual BCL2/BCLxL. For KPUM-MS3, KPUM-UH1, and STR-428 cells, the IC50s values are 26 nM, 17 nM, and 170 nM , respectively...
|
| T5S0993 |
Kurarinone
|
34981-26-5
|
99.72%
|
|
|
Kurarinone, a flavanoid derived from shrub Sophora flavescens,Kurarinone exhibits anti-tumor, estrogenic, and anti-inflammatory activities, it also shows strong ...
|
| T3344 |
Ciwujianoside B
|
114902-16-8
|
99.73%
|
|
|
Ciwujianoside B (acanthopanax senticosides B) is the main component of Acanthopanax, can relieve fatigue, enhance memory, and improve human cognition.
|
| T5108 |
ML311
|
315698-17-0
|
99.75%
|
|
|
ML311 is a selective inhibitor of the Mcl-1/Bim interaction.
|
| T2119 |
Venetoclax
|
1257044-40-8
|
99.78%
|
|
|
Venetoclax (ABT-199) is a Bcl-2 inhibitor (Ki<0.01 nM) with potent, selective, and orally active properties. Venetoclax has a 3-order-of-magnitude lower affinity...
|
| T14561 |
BI-3812
|
2166387-64-8
|
99.79%
|
|
|
BI-3812 is an inhibitor of BCL6. Which inhibiting the BTB domain of BCL6 (IC50: 3 nM). BI-3812 also has antitumor activity.
|
| T2S2362 |
Dehydrocorydaline nitrate
|
13005-09-9
|
99.79%
|
|
|
1. Dehydrocorydaline(DHC) not only inhibits antibody-mediated allergic reactions but also influences cell-mediated allergic reactions, and the inhibitory effect ...
|
| TN5263 |
1-[2,4-Dihydroxy-6-methoxy-3-(3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)-2-propen-1-one
|
569-83-5
|
99.79%
|
|
|
1-[2,4-Dihydroxy-6-methoxy-3-(3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)-2-propen-1-one (Xanthohumol) , prenylchacone flavonoid, is a natural product with...
|
| T6518 |
Gossypol
|
303-45-7
|
99.8%
|
|
|
Gossypol (BL 193) Acetate is a polyphenolic aldehyde that permeates cells and acts as an inhibitor for several dehydrogenase enzymes.
|
| T4085 |
Paris saponin VII
|
68124-04-9
|
99.83%
|
|
|
Paris saponin VII (Dioscini) shows inhibitory effects on cell proliferation.
|
| T79404 |
A09-003
|
2911646-14-3
|
99.84%
|
|
|
A09-003 is a novel cell cycle protein-dependent kinase-9 CDK-9 inhibitor.A09-003 inhibits the proliferation of a variety of leukemia cell lines and inhibits the ...
|
| T12041 |
MIM1
|
509102-00-5
|
99.84%
|
|
|
MIM1 (Inhibitor of Mcl-1) is an myeloid cell factor 1 (Mcl-1) inhibitor.
|
| TN1677 |
Gartanin
|
33390-42-0
|
99.85%
|
|
|
Gartanin is an androgen receptor degradation enhancer, it is also a potential neuroprotective agent against glutamate-induced oxidative injury partially through ...
|
| T14834 |
BT2
|
34576-94-8
|
99.86%
|
|
|
BT2, a BCKDC kinase (BDK) inhibitor, exhibits an IC50 of 3.19 μM and functions as a potent, selective Mcl-1 inhibitor with a Ki value of 59 μM. Its interaction w...
|
