| T5810 |
TABERSONINE HYDROCHLORIDE
|
29479-00-3
|
98%
|
|
|
TABERSONINE HYDROCHLORIDE is a natural product extracted from the bean of Voacanga africana, is a potent inhibitor against Aβ(1 42) aggregation and toxicity.
|
| TN1341 |
8-Deoxygartanin
|
33390-41-9
|
98%
|
|
|
8-Deoxygartanin is a butyrylcholinesterase (BChE) selective inhibitor, it exhibits significant inhibition of self-induced α2-amyloid (Aα2) aggregation, it has mu...
|
| T38469 |
(Rac)-Z-Phe-Phe-FMK
|
108005-94-3
|
98%
|
|
|
(Rac)-Z-Phe-Phe-FMK (Cathepsin L-IN-2) is a cathepsin L inhibitor that inhibits the tendency of β-amyloid to induce apoptotic changes .
|
| T6562 |
Latrepirdine dihydrochloride
|
97657-92-6
|
98%
|
|
|
Latrepirdine dihydrochloride (Dimebolin dihydrochloride) is an orally active, and neuroactive antagonist of multiple drug targets, including histamine receptors,...
|
| T22932L |
LPYFD-NH2 acetate
|
|
98%
|
|
|
LPYFD-NH2 acetate shows some inhibitory effect on the aggregation of Abeta(1-42).
|
| T7680 |
GSNKGAIIGLM(131602-53-4(free base))
|
T7680
|
98%
|
|
|
GSNKGAIIGLM(131602-53-4(free base)) (Amyloid beta-peptide(25-35)) is the fragment Aβ(25-35) of the Alzheimer's amyloid β-peptide.
|
| T77054 |
Lecanemab
|
1260393-98-3
|
98%
|
Lecanemab
|
|
Lecanemab (BAN-2401), an IgG1 monoclonal antibody targeting soluble aggregated amyloid beta (Aβ), demonstrates efficacy across Aβ oligomers, protofibrils, and in...
|
| T77042 |
Aducanumab
|
1384260-65-4
|
98%
|
Aducanumab
|
|
Aducanumab (BIIB037), A selective human immunoglobulin gamma-1 (IgG1) monoclonal antibody, targets the clustered form of amyloid beta (Aβ). Aducanumab shows brai...
|
| T2873 |
Ginsenoside Rg2
|
52286-74-5
|
98%
|
|
|
Ginsenoside Rg2 (Chikusetsusaponin I) is one of the major active components of ginseng, act as an NF-κB inhibitor.
|
| T6202 |
DAPT
|
208255-80-5
|
98%
|
|
|
DAPT (LY-374973) is a γ-secretase inhibitor that inhibits total Aβ and Aβ42 (IC50=115/200 nM) and is orally active. DAPT is also a Notch inhibitor. DAPT induces ...
|
| TQ0026 |
MDR-1339
|
1018946-38-7
|
98%
|
|
|
MDR-1339 (DWK-1339) is an orally active and blood-brain-barrier-permeable inhibitor of amyloid-β (Aβ) aggregation.
|
| TP1935L1 |
RAGE antagonist peptide acetate
|
TP1935L1
|
98%
|
|
|
RAGE antagonist peptide acetate is an advanced antagonist of glycation end products (RAGE). RAGE antagonist peptide acetate possesses anti-tumor and anti-inflamm...
|
| TP1229 |
β-Amyloid (1-15)
|
183745-81-5
|
98%
|
|
|
β-Amyloid (1-15) (Amyloid β-Protein (1-15)) is a fragment of β-amyloid protein used in the study of Alzheimer's disease.
|
| T7905 |
PBD-150
|
790663-33-1
|
100%
|
|
|
PBD-150 is an inhibitor of human glutaminyl cyclase (hQC) Y115E-Y117E variant( ki : 490 nM)
|
| T7562 |
β-Amyloid (31-35)
|
149385-65-9
|
100%
|
|
|
β-Amyloid (31-35) (β-Amyloid 31-35) is the shortest sequence of native Amyloid-β peptide.
|
| T22204 |
LY 2389575 hydrochloride
|
885104-09-6
|
100%
|
|
|
LY2389575 hydrochloride is an mGlu3 negative allosteric modulator (NAM) that is selective and non-competitive, with an IC50 value of 190 nM. LY2389575 hydrochlor...
|
| TP1866L |
β-amyloid 1-11 acetate(190436-05-6 free base)
|
TP1866L
|
100%
|
|
|
β-amyloid 1-11 acetate is a fragment of Amyloid-β peptide, maybe used in the research of neurological disease.
|
| T14673 |
BMS 299897
|
290315-45-6
|
100%
|
|
|
BMS 299897 is a sulfonamide γ-secretase inhibitor. It has an IC50 of 7 nM for Aβ production inhibition in HEK293 cells stably overexpressing amyloid precursor pr...
|
| T0795 |
Rutin
|
153-18-4
|
95%
|
|
|
Rutin (Quercetin 3-O-rutinoside), a flavonoid, has a variety of biological activities including antiallergic, anti-inflammatory, antiproliferative, and anticarci...
|
| T28441 |
PPI-1019
|
290828-45-4
|
95.16%
|
|
|
PPI-1019 is an APP (β-amyloid A4) inhibitor for the treatment of neurological disorders and the study of Alzheimer's disease (AD).
|
