CETP

Cholesteryl ester transfer protein (CETP), also called plasma lipid transfer protein, is a plasma protein that facilitates the transport of cholesteryl esters and triglycerides between the lipoproteins. It collects triglycerides from very-low-density (VLDL) or low-density lipoproteins (LDL) and exchanges them for cholesteryl esters from high-density lipoproteins (HDL), and vice versa. Most of the time, however, CETP does a heteroexchange, trading a triglyceride for a cholesteryl ester or a cholesteryl ester for a triglyceride.

Cat. No.	製品名	CAS No.	Purity
T27719	KD-026	913541-47-6	98%
T27719	KD-026 (SLx 4090), a microsomal triglyceride transfer protein (MTP) inhibitor(IC50 = 8.0 nM), is used in type 2 diabetes studies.
T16266	NAMI-A	201653-76-1	98%
T16266	NAMI-A is a ruthenium-based compound with selective activity against tumor metastasis.NAMI-A inhibits cancer cell adhesion and migration.
T1928	Anacetrapib	875446-37-0	97.09%
T1928	Anacetrapib (MK-0859) (MK0859) is an effective, specific, reversible rhCETP and mutant CETP(C13S) inhibitor (IC50: 7.9 nM and 11.8 nM). Anacetrapib reduces the t...
T6048	Dalcetrapib	211513-37-0	97.99%
T6048	Dalcetrapib (RO4607381), a rhCETP inhibitor (IC50=0.2 μM), increases the plasma HDL cholesterol.
T6262	Evacetrapib	1186486-62-3	98.53%
T6262	Evacetrapib (LY2484595) (LY2484595) is a potent and selective inhibitor of CETP with IC50 of 5.5 nM, elevates HDL cholesterol without increases in aldosterone or...
T30506	BMS-212122	194213-64-4	98.70%
T30506	BMS-212122 (UNII-0Z473OO6GB) is a potent inhibitor of microsomal triglyceride transfer protein (MTP) and has shown hypolipidemic effects in animal studies.BMS-21...
T2499	Torcetrapib	262352-17-0	98.91%
T2499	Torcetrapib (CP-529414) is a cholesteryl ester transfer protein (CETP) inhibitor that reduces the heterotypic transfer of cholesteryl ester from HDL to LDL and/o...
T15006	Dirlotapide	481658-94-0	99.20%
T15006	Dirlotapide (CP742033) is an intestinal selective microsomal triglyceride transfer protein (MTP) inhibitor. It reduces body weight in diabetic dogs.Dirlotapide r...
T6267	Lomitapide	182431-12-5	99.23%
T6267	Lomitapide (AEGR-733) is a small molecule inhibitor of microsomal triglyceride transfer protein (MTP), an enzyme located in the lumen of the endoplasmic reticulu...
T28225	Obicetrapib	866399-87-3	99.26%
T28225	Obicetrapib (AMG-899) is an inhibitor of cholesteryl ester transfer protein.
T31992	Granotapide	594842-13-4	99.34%
T31992	Granotapide is a microsomal triglyceride transfer protein (MTP) inhibitor that treats and rather prevents atherosclerosis, coronary artery disease, metabolic syn...
T2545	Lomitapide Mesylate	202914-84-9	99.65%
T2545	Lomitapide Mesylate (BMS-201038 mesylate) is a methanesulfonic acid form of lomitapide, a small molecule inhibitor of microsomal triglyceride transfer protein.
T15004	CP-532623	261947-38-0	98%
T15004	CP-532623, a close structural analog of Torcetrapib, is a CETP inhibitor with highly lipophilic properties. It elevates high-density lipoprotein cholesterol.
T15570	Implitapide	177469-96-4	98%
T15570	Implitapide is an inhibitor of microsomal triglyceride transfer protein (MTP).
T13079	TAP311	T13079	98%
T13079	TAP311 is an inhibitor of cholesteryl ester transfer protein (CETP)(IC50 of 62 nM).