CRISPR/Cas9

Cas9 (CRISPR associated protein 9, formerly called Cas5, Csn1, or Csx12) is a 160 kilodalton protein which plays a vital role in the immunological defense of certain bacteria against DNA viruses and plasmids, and is heavily utilized in genetic engineering applications. Its main function is to cut DNA and thereby alter a cell's genome.

Cat. No.	製品名	CAS No.	Purity
T22279	BRD0539	1403838-79-8	98.03%
T22279	BRD0539 is a cell-permeable spCas9 inhibitor that blocks the binding of spCas9 to DNA and inhibits Streptococcus pyogenes Cas9 (SpCas9).
T6872	L755507	159182-43-1	99.04%
T6872	L755507 is an effective, selective agonist of β3-AR（IC50=35 nM）.
T6062	Brefeldin A	20350-15-6	99.26%
T6062	Brefeldin A (Cyanein) belongs to the class of macrolide antibiotics and is an ATPase inhibitor (IC50=0.2 μM). Brefeldin A can induce tumor cell differentiation a...
T2802	Nocodazole	31430-18-9	99.34%
T2802	Nocodazole (Oncodazole) is a reversible inhibitor of microtubule polymerization and an inhibitor of Bcr-Abl. Nocodazole has antitumor activity, blocks the cell c...
T1724	SCR7 pyrazine	14892-97-8	99.83%
T1724	SCR7 pyrazine (SCR7) enhances CRISPR-Cas9-mediated homology-directed repair (HDR) efficiency in vitro up to 19-fold. Inhibits nonhomologous end-joining (NHEJ).
T6276	KU-57788	503468-95-9	99.87%
T6276	NU7441 (KU-57788 (NU7441)) is a highly effective and specific DNA-PK inhibitor (IC50: 14 nM).
T1416	Zidovudine	30516-87-1	99.91%
T1416	Zidovudine (ZDV) is a synthetic dideoxynucleoside. After intracellular phosphorylation to its active metabolite, zidovudine inhibits DNA polymerase, resulting in...
T3340	SCR7	1533426-72-0
T3340	SCR7, a specific DNA Ligase IV inhibitor, blocks nonhomologous end-joining (NHEJ).