| T14885 |
CBS9106
|
1076235-04-5
|
98%
|
|
|
CBS9106 (SL-801) is a reversible oral inhibitor of CRM1 with CRM1 degrading and antitumor activities. CBS9106 arrests the cell cycle and inducing apoptosis in a ...
|
| T2425 |
KPT185
|
1333151-73-7
|
|
|
|
KPT185 (KPT 185) is a selective CRM1 inhibitor, inducing apoptosis, cell-cycle arrest.
|
| T6074 |
KPT276
|
1421919-75-6
|
100%
|
|
|
KPT276 (KPT 276) is an orally bioavailable selective inhibitor of nuclear export (SINE) that irreversibly bind to CRM1 and block the function of CRM1.
|
| T6123 |
Verdinexor
|
1392136-43-4
|
98.79%
|
|
|
Verdinexor (KPT-335) (KPT-335), a specific XPO1/CRM1 inhibitor, are orally bioavailable.
|
| T1844 |
KPT330,(E)-
|
1421923-86-5
|
99.26%
|
|
|
(E)-RN (KPT 330) is a CRM1-selective inhibitor of nuclear export. It inhibits protein trafficking from the nucleus and induces cell cycle arrest and apoptosis in...
|
| T15735 |
Leptomycin B
|
87081-35-4
|
99.71%
|
|
|
Leptomycin B (LMB) is a potent inhibitor of the nuclear export of proteins and is a potent antifungal antibiotic blocking the eukaryotic cell cycle. Leptomycin B...
|
| T6106 |
Selinexor (KPT-330)
|
1393477-72-9
|
99.85%
|
|
|
Selinexor (KPT-330) is a small molecule inhibitor of CRM1 with selective and oral activity. Selinexor blocks the cell cycle, induces apoptosis, and has antitumor...
|
| T11837 |
Leptomycin A
|
87081-36-5
|
98%
|
|
|
Leptomycin A, a metabolite derived from Streptomyces, acts as an inhibitor of CRM1 (exportin 1) and effectively suppresses HIV-1 replication. Compared to Leptomy...
|
| T81936 |
LFS-1107
|
1799330-91-8
|
98%
|
|
|
LFS-1107, a reversible CRM1 inhibitor (Kd: 12.5 pM), selectively targets and eliminates ENKTL cells, offering potential for cancer research applications [1].
|
| T79655 |
CRM1-IN-2
|
|
98%
|
|
|
CRM1-IN-2 (Compound KL2) is a noncovalent inhibitor that targets CRM1, localizing it to the nuclear periphery, depleting its nuclear presence, and inhibiting its...
|
| T79654 |
CRM1-IN-1
|
|
98%
|
|
|
CRM1-IN-1 (Compound KL1), a noncovalent inhibitor of CRM1, promotes nuclear degradation of CRM1 with an IC50 of 0.27 μM, inhibits CRM1-mediated nuclear export, s...
|
