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Cannabinoid Receptor

Cannabinoid receptors are of a class of cell membrane receptors in the G protein-coupled receptor superfamily. As is typical of G protein-coupled receptors, the cannabinoid receptors contain seven transmembrane spanning domains. Cannabinoid receptors are activated by three major groups of ligands: endocannabinoids, produced by the mammillary body;[citation needed] plant cannabinoids (such as cannabidiol, produced by the cannabis plant); and synthetic cannabinoids (such as HU-210). All of the endocannabinoids and phytocannabinoids (plant based cannabinoids) are lipophilic, such as fat soluble compounds.
Cat. No. 製品名 CAS No. Purity Chemical Structure
T22984 MJ 15 944154-76-1 98%
MJ 15 is a CB1 receptor antagonist with specificity for the study of obesity-induced diseases.
T14011 2-Arachidonoylglycerol 53847-30-6 98%
In the central nervous system, 2-Arachidonoylglycerol is a second endogenous cannabinoid ligand
T1519 Rimonabant hydrochloride 158681-13-1 98%
Rimonabant hydrochloride (SR 141716A) is a cannabinoid receptor antagonist, binding selectively to central cannabinoid receptors (CB1) with high affinity.
T64394 GW 833972A 1092502-33-4 98%
GW 833972A is a selective CB2 receptor agonist.GW 833972A has an inhibitory effect on induced neural depolarization and on citric acid-induced cough in an animal...
T61562 CB1R Allosteric modulator 3 2633686-36-7 98%
CB1R Allosteric modulator 3 is a potent CB1R modulator.CB1R Allosteric modulator 3 inhibits cAMP and β-Arrestin, and can be used for the study of obesity and nic...
T62761 CB1 agonist 1 851212-80-1 98%
CB1 agonist 1 is a potent CB1 agonist with a pIC50 value of 5.7 for CB1 receptors.CB1 agonist 1 can be used to study brain disorders, pain, and inflammation.
T79909 AEF0117 1610878-71-1 98%
AEF0117, a signaling-specific inhibitor of cannabinoid receptor 1 (CB1-SSi), inhibits cannabinoid self-administration and behavioral disorders associated with TH...
T61989 CB1R antagonist 1 334668-69-8 98%
CB1R antagonist 1 is a potent CB1R antagonist that can be used to study diseases related to the nervous system.
T19705 JTE-907 282089-49-0 100%
JTE-907 is a CB2 receptor inverse agonist with high selectivity and oral activity.JTE-907 exhibits anti-inflammatory activity in vivo.
T0851 Pregnenolone 145-13-1 100%
Pregnenolone (Arthenolone) is an endogenous steroid hormone synthesized from cholesterol, used in the treatment of Alzheimer's disease.
T67896 CB2R/FAAH modulator-1 928892-60-8 100%
CB2R/FAAH modulator-1, a cannabinoid type 2 receptor (CB2R) agonist, is also a fatty acid amide hydrolase (FAAH) inhibitor (IC50=4 μM) that reduces the productio...
TN2268 Tetrahydromagnolol 20601-85-8 100%
Tetrahydromagnolol can activate cannabinoid (CB) receptors.
T3530 Otenabant 686344-29-6 100%
Otenabant (CP-945598) has been investigated for the treatment of Obesity.
T8511 TM38837 1253641-65-4 100%
TM38837 is an antagonist of cannabinoid receptor type 1 (CB1), with potential for the treatment of obesity and type 2 diabetes.
T24771 SCH-336 447459-51-0 95.01%
SCH-336 is a CB2 receptor agonist (Ki-1.8 nM, EC50-2 nM) with effective, selective, and oral activity. SCH-336 is also bioactive against CB1 receptor, and is 100...
TN5131 Tetrahydrocannabivarin 31262-37-0 96.30%
Tetrahydrocannabivarin (CRM) is a neutral cannabis receptor subtype (CB1) receptor antagonist, it can increases neural responding to rewarding and aversive stimu...
T14302 Olorinab 1268881-20-4 97.13%
Olorinab (APD 371) (APD 371) is a highly potent, selective and fully efficacious cannabinoid receptor type 2 (CB2) agonist. With an EC50 of 6.2 nM for hCB2.
T9114 β-Caryophyllene 87-44-5 97.31%
β-Caryophyllene ((-)-(E)-Caryophyllene) acts as an CB2 receptor agonist.
T1915 AM251 183232-66-8 97.88%
AM251 is a effective CB1 receptor antagonist (IC50/Ki: 8 /7.49 nM) that displays 306-fold selectivity over CB2 receptors; also effective GPR55 agonist (EC50: 39 ...
T3S0738 Yangonin 500-62-9 98%
Yangonin (Y100550) is a novel CB receptor ligand, it exhibits affinity for the human recombinant CB receptor. Yangonin (Y100550) could be a valuable candidate fo...
MJ 15
T22984
MJ 15 is a CB1 receptor antagonist with specificity for the study of obesity-induced diseases.
2-Arachidonoylglycerol
T14011
In the central nervous system, 2-Arachidonoylglycerol is a second endogenous cannabinoid ligand
Rimonabant hydrochloride
T1519
Rimonabant hydrochloride (SR 141716A) is a cannabinoid receptor antagonist, binding selectively to central cannabinoid receptors (CB1) with high affinity.
GW 833972A
T64394
GW 833972A is a selective CB2 receptor agonist.GW 833972A has an inhibitory effect on induced neural depolarization and on citric acid-induced cough in an animal...
CB1R Allosteric modulator 3
T61562
CB1R Allosteric modulator 3 is a potent CB1R modulator.CB1R Allosteric modulator 3 inhibits cAMP and β-Arrestin, and can be used for the study of obesity and nic...
CB1 agonist 1
T62761
CB1 agonist 1 is a potent CB1 agonist with a pIC50 value of 5.7 for CB1 receptors.CB1 agonist 1 can be used to study brain disorders, pain, and inflammation.
AEF0117
T79909
AEF0117, a signaling-specific inhibitor of cannabinoid receptor 1 (CB1-SSi), inhibits cannabinoid self-administration and behavioral disorders associated with TH...
CB1R antagonist 1
T61989
CB1R antagonist 1 is a potent CB1R antagonist that can be used to study diseases related to the nervous system.
JTE-907
T19705
JTE-907 is a CB2 receptor inverse agonist with high selectivity and oral activity.JTE-907 exhibits anti-inflammatory activity in vivo.
Pregnenolone
T0851
Pregnenolone (Arthenolone) is an endogenous steroid hormone synthesized from cholesterol, used in the treatment of Alzheimer's disease.
CB2R/FAAH modulator-1
T67896
CB2R/FAAH modulator-1, a cannabinoid type 2 receptor (CB2R) agonist, is also a fatty acid amide hydrolase (FAAH) inhibitor (IC50=4 μM) that reduces the productio...
Tetrahydromagnolol
TN2268
Tetrahydromagnolol can activate cannabinoid (CB) receptors.
Otenabant
T3530
Otenabant (CP-945598) has been investigated for the treatment of Obesity.
TM38837
T8511
TM38837 is an antagonist of cannabinoid receptor type 1 (CB1), with potential for the treatment of obesity and type 2 diabetes.
SCH-336
T24771
SCH-336 is a CB2 receptor agonist (Ki-1.8 nM, EC50-2 nM) with effective, selective, and oral activity. SCH-336 is also bioactive against CB1 receptor, and is 100...
Tetrahydrocannabivarin
TN5131
Tetrahydrocannabivarin (CRM) is a neutral cannabis receptor subtype (CB1) receptor antagonist, it can increases neural responding to rewarding and aversive stimu...
Olorinab
T14302
Olorinab (APD 371) (APD 371) is a highly potent, selective and fully efficacious cannabinoid receptor type 2 (CB2) agonist. With an EC50 of 6.2 nM for hCB2.
β-Caryophyllene
T9114
β-Caryophyllene ((-)-(E)-Caryophyllene) acts as an CB2 receptor agonist.
AM251
T1915
AM251 is a effective CB1 receptor antagonist (IC50/Ki: 8 /7.49 nM) that displays 306-fold selectivity over CB2 receptors; also effective GPR55 agonist (EC50: 39 ...
yangonin
T3S0738
Yangonin (Y100550) is a novel CB receptor ligand, it exhibits affinity for the human recombinant CB receptor. Yangonin (Y100550) could be a valuable candidate fo...
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