| T7497 |
C3a (70-77)
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C3a 70-77 is an octapeptide corresponding to the COOH terminus of C3a.
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| T64388 |
3-Phenoxybenzaldehyde
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3-Phenoxybenzaldehyde is a complement (classical pathway) inhibitor with IC50 of 1388μM.
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| T38332 |
Complement factor D-IN-2
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Complement factor D-IN-2 is an inhibitor of complement factor D extracted from patent WO2015130838A1, compound 190. Complement factor D-IN-2 targets factor D and...
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| TP2180L |
Compstatin control peptide acetate
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Compstatin control peptide acetate is an inhibitor of complement protein C3 by binding and inhibiting the cleavage of complement C3.
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| T17250 |
W-54011
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W-54011 is a potent non-peptide C5a receptor antagonist. W-54011 inhibits the binding of 125I-labeled C5a to human neutrophils (Ki: 2.2 nM). W-54011 inhibits C5a...
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| T9915 |
Eculizumab
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Eculizumab is a recombinant humanized monoclonal antibody against the complement protein C5
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| T7776 |
ADH-503
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ADH-503 is a potent agonist of the integrin CD11b to mitigate myeloid cell immunosuppression.
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| TP1304 |
Compstatin
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Compstatin, a cyclic tridecapeptide, which was originally discovered from phage-display libraries, is a highly potent and selective C3 inhibitor.
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| T7497L |
C3a 70-77 2TFA(63555-63-5(free base))
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C3a 70-77 2TFA is an octapeptide corresponding to the COOH terminus of C3a.
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| T38287 |
C3a Receptor Agonist
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C3a Receptor Agonist binds the G protein-coupled C3a receptors (C3aRs) in the immune system complement pathway. Activation of C3aR prevents neutrophils from bein...
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| T3638 |
Leukadherin-1
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Leukadherin-1 is an allosteric activator of CD11b/CD18. Increasing CD11b/CD18-dependent cell adhesion to fibrinogen, Decreasing leukocyte motility and transendot...
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| T12851 |
SB290157 trifluoroacetate
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SB290157 trifluoroacetate is a potent and selective antagonist of C3a receptor(IC50 of 200 nM).
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| T9316 |
JR14a
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JR14a is a potent antagonist of human complement C3a receptor.
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| T12506L1 |
PMX 205 acetate(514814-49-4 free base)
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PMX 205 acetate is an antagonist of complement C5a receptor (C5aR; CD88).
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| T60151 |
CP-447697
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CP-447697 is a lipophilic C5a receptor antagonist with an IC50 value of 31 nM. CP-447697 can be used for the research of inflammation.
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| T9189 |
Iptacopan hydrochloride
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LNP023 hydrochloride is an orally bioavailable, highly potent and highly selective factor B inhibitor with an IC50 of 10 nM. LNP023 shows direct, reversible, and...
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| T0945 |
Cyclosporin A
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Cyclosporine A is a Calcineurin Inhibitor Immunosuppressant. The mechanism of action of cyclosporine is as a Calcineurin Inhibitor, and Cytochrome P450 3A4 Inhib...
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| T60161 |
CP-289
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CP-289 is a potent C5a receptor antagonist with IC50 of 1 μM.
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| T8509 |
Danicopan
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Danicopan (ACH-4471) is a selective, orally active small molecule factor D inhibitor with high binding affinity to human factor D, with a Kd value of 0.54 nM. Da...
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| T8223 |
Avacopan
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Avacopan is an orally administered small-molecule C5aR ( IC50 : 0.1 nM.)antagonist that blocks the effects of C5a and prevents the development of GN induced by a...
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| T1076 |
Dexamethasone
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Dexamethasone is a glucocorticoid receptor agonist and an IL receptor modulator.Dexamethasone inhibits production of exosomes containing inflammatory microRNA-15...
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| TP2334 |
PMX 53 acetate(219639-75-5 free base)
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PMX-53 is a potent and orally active CD88 (C5aR) antagonist (IC50: 20 nM) and inhibits C5a-induced neutrophil myeloperoxidase release and chemotaxis with IC50 va...
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| TP1305L |
LEP(116-130)(mouse)TFA(258276-95-8 free base)
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LEP(116-130)(mouse) is a synthetic leptin peptide fragment.
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| T9695L |
POT-4 acetate
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POT-4 acetate inhibits Complement C3 activation. POT-4 acetate can be used for studies about age-related macular degeneration.
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| TP2296L |
TLQP 21 acetate
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TLQP 21 acetate is a potent agonist of G-protein-coupled receptor complement-3a receptor 1 (C3aR1). The EC50 values are 10.3 μM for mouse and 68.8 μM for human...
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| T13379 |
(Z)-Leukadherin-1
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(Z)-Leukadherin-1 is an allosteric agonist of CD11b.
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